SCHEMBL28450397

SCHEMBL28450397

CC[SiH](CC)CCCCOCC1CO1

nearest known ligand 0.64

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.64
ALDH1A1 P00352 5/20 0.62
TDP1 Q9NUW8 1/20 0.62
SMN1; SMN2 Q16637 1/20 0.61
MAPK1 P28482 1/20 0.40
PDK1 Q15118 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23701034 0.95 SMN1; SMN2 (0.63) TSHRALDH1A1TDP1SMN1; SMN2MAPK1
SCHEMBL28619228 0.83 ALDH1A1 (0.65) TSHRALDH1A1TDP1SMN1; SMN2MAPK1
SCHEMBL28411919 0.81 TSHR (0.69) TSHRALDH1A1TDP1SMN1; SMN2MAPK1
SCHEMBL17549552 0.80 TSHR (1.00) TSHRALDH1A1TDP1SMN1; SMN2MAPK1
SCHEMBL17549553 0.80 TSHR (1.00) TSHRALDH1A1TDP1SMN1; SMN2MAPK1
SCHEMBL21272 0.80 TSHR (1.00) TSHRALDH1A1TDP1SMN1; SMN2MAPK1
SCHEMBL13974192 0.80 TSHR (1.00) TSHRALDH1A1TDP1SMN1; SMN2MAPK1
SCHEMBL17549551 0.80 TSHR (1.00) TSHRALDH1A1TDP1SMN1; SMN2MAPK1
SCHEMBL9392314 0.80 TSHR (0.67) TSHRALDH1A1TDP1SMN1; SMN2MAPK1
SCHEMBL43463 0.79 TSHR (0.60) TSHRALDH1A1TDP1SMN1; SMN2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106661383-B Pressure sensitive adhesive composition 株式会社LG化学 2020-09-01 CN disclosed