Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
| ▸ | CTRC | Q99895 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | SHBG | P04278 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | CTSG | P08311 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14601491 | 0.81 | PRSS1 (0.37) | PRSS1CTRCF2ELANECTSG | |
| SCHEMBL6427227 | 0.80 | PRSS1 (0.41) | PRSS1CTRCF2CYP19A1SHBG | |
| SCHEMBL18239488 | 0.80 | MEN1 (0.36) | PRSS1CTRCF2CYP19A1MEN1 | |
| SCHEMBL7053913 | 0.80 | PRSS1 (0.41) | PRSS1CTRCF2CYP19A1SHBG | |
| SCHEMBL6427222 | 0.80 | PRSS1 (0.41) | PRSS1CTRCF2CYP19A1SHBG | |
| SCHEMBL6295869 | 0.80 | PRSS1 (0.41) | PRSS1CTRCF2CYP19A1SHBG | |
| SCHEMBL2082259 | 0.73 | PRSS1 (0.34) | PRSS1CTRCF2 | |
| SCHEMBL9616924 | 0.70 | F2 (0.42) | PRSS1CTRCF2MEN1KMT2A | |
| SCHEMBL5480226 | 0.69 | F2 (0.36) | PRSS1CTRCF2ELANECTSG | |
| SCHEMBL16014107 | 0.68 | PRSS1 (0.40) | PRSS1CTRCF2ALDH1A1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2203434-B1 | METHOD OF PREPARING (6R)-3-HEXYL-4-HYDROXY-6-UNDECYL-5,6-DIHYDROPYRAN-2-ONE, AND INTERMEDIATE USED IN THE METHOD | HANMI HOLDINGS CO LTD (KR) | 2012-08-29 | — | — | EP | disclosed |
| US-8242288-B2 | Method of preparing (6R)-3-hexyl-4-hydroxy-6-undecyl-5, 6-dihydropyran-2-one, and intermediate used in the method | HANMI HOLDINGS CO., LTD. (KR) | 2012-08-14 | — | — | US | disclosed |
| US-20100274029-A1 | METHOD OF PREPARING (6R)-3-HEXYL-4-HYDROXY-6-UNDECYL-5, 6-DIHYDROPYRAN-2-ONE, AND INTERMEDIATE USED IN THE METHOD | HANMI PHARM. CO., LTD. (KR) | 2010-10-28 | — | — | US | disclosed |
| EP-2203434-A2 | METHOD OF PREPARING (6R)-3-HEXYL-4-HYDROXY-6-UNDECYL-5,6-DIHYDROPYRAN-2-ONE, AND INTERMEDIATE USED IN THE METHOD | Hanmi Pharm. Co., Ltd. (KR) | 2010-07-07 | — | — | EP | disclosed |
| WO-2009057938-A2 | METHOD OF PREPARING (6R)-3-HEXYL-4-HYDROXY-6-UNDECYL-5,6-DIHYDROPYRAN-2-ONE, AND INTERMEDIATE USED IN THE METHOD | HANMI PHARM. CO., LTD. (KR) | 2009-05-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100274029-A1 | METHOD OF PREPARING (6R)-3-HEXYL-4-HYDROXY-6-UNDECYL-5, 6-DIHYDROPYRAN-2-ONE, AND INTERMEDIATE USED IN THE METHOD | DHCR7, DHPS, CYP8B1 | PRSS1 3885/4885CTRC 1626/4885F2 2031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.