SCHEMBL2845089

SCHEMBL2845089

Cc1cc(Br)c(S(=O)(=O)O)cc1Br

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
TSHR P16473 4/20 0.43
LMNA P02545 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.40
KMT2A Q03164 2/20 0.37
NPC1 O15118 1/20 0.37
NR2F2 P24468 1/20 0.37
NOD2 Q9HC29 1/20 0.37
HSD17B10 Q99714 1/20 0.37
BCHE P06276 1/20 0.36
CES1 P23141 1/20 0.36
MEN1 O00255 1/20 0.36
NSD2 O96028 1/20 0.36
PKM P14618 1/20 0.36
BLM P54132 1/20 0.36
RXFP1 Q9HBX9 1/20 0.36
RAB9A P51151 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2846267 0.91 TSHR (0.43) POLBL3MBTL1TSHRLMNASMN1; SMN2
SCHEMBL4347833 0.86 CA1 (0.40) POLBL3MBTL1TSHRLMNASMN1; SMN2
Hydrochloric Acid SCHEMBL28121331 0.85 POLB (0.50) POLBL3MBTL1TSHRLMNASMN1; SMN2
SCHEMBL10599860 0.82 POLB (0.40) POLBL3MBTL1TSHRSMN1; SMN2KMT2A
SCHEMBL11871669 0.81 CA1 (0.42) POLBL3MBTL1TSHRLMNAKMT2A
SCHEMBL5082288 0.79 CA1 (0.41) POLBL3MBTL1TSHRLMNAKMT2A
SCHEMBL11746057 0.79 TSHR (0.41) POLBL3MBTL1TSHRLMNAKMT2A
SCHEMBL18726107 0.79 TSHR (0.60) POLBL3MBTL1TSHRLMNASMN1; SMN2
Water SCHEMBL7908328 0.77 TSHR (0.59) POLBL3MBTL1TSHRLMNASMN1; SMN2
SCHEMBL25257871 0.76 L3MBTL1 (0.45) POLBL3MBTL1TSHRLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120251919-A1 POLYARYLENE-BASED COPOLYMER AND USES THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-04 US disclosed
EP-2489690-A1 POLYARYLENE COPOLYMER AND USES THEREOF Sumitomo Chemical Company Limited (JP) 2012-08-22 EP disclosed
US-20100129729-A1 CEOSSLINKED AROMATIC POLYMER, POLYMER ELECTROLYTE,CATALYST INK, POLYMER ELECTROLYTE MEMBRANE, MEMBRANE-ELECTRODE ASSEMBLY AND FUEL CELL SUMITOMO CHEMICAL COMPANY ,LIMITED 2010-05-27 US disclosed
EP-2147943-A1 CROSSLINKED AROMATIC POLYMER, POLYMER ELECTROLYTE, CATALYST INK, POLYMER ELECTROLYTE MEMBRANE, MEMBRANE-ELECTRODE ASSEMBLY AND FUEL CELL Sumitomo Chemical Company, Limited (JP) 2010-01-27 EP disclosed
US-20090253015-A1 POLYARYLENE BLOCK COPOLYMER AND USE THEREOF SUMITOMO CHEMICAL COMPANY ,LIMITED (JP) 2009-10-08 US disclosed