Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.59 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.59 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.59 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.59 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | PI4KA | P42356 | 1/20 | 0.53 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.53 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.53 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.53 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.48 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.48 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.48 |
| ▸ | AHCY | P23526 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6905183 | 0.88 | FGFR1 (0.63) | FGFR1SLC22A6ADORA2AADORA2BADORA1 | |
| SCHEMBL6897575 | 0.83 | FGFR1 (0.56) | FGFR1SLC22A6ADORA2AADORA2BADORA1 | |
| SCHEMBL886938 | 0.83 | CYP3A4 (0.67) | FGFR1SLC22A6ADORA2AADORA2BADORA1 | |
| SCHEMBL6898720 | 0.83 | FGFR1 (0.56) | FGFR1SLC22A6ADORA2AADORA2BADORA1 | |
| SCHEMBL6898237 | 0.83 | FGFR1 (0.56) | FGFR1SLC22A6ADORA2AADORA2BADORA1 | |
| SCHEMBL6690541 | 0.83 | FGFR1 (0.56) | FGFR1SLC22A6ADORA2AADORA2BADORA1 | |
| SCHEMBL6904146 | 0.83 | FGFR1 (0.56) | FGFR1SLC22A6ADORA2AADORA2BADORA1 | |
| SCHEMBL6905129 | 0.82 | FGFR1 (0.52) | FGFR1SLC22A6ADORA2AADORA2BADORA1 | |
| SCHEMBL28607691 | 0.82 | ADORA2A (0.51) | ADORA2AADORA2BADORA1CYP3A4PI4KA | |
| SCHEMBL15941844 | 0.81 | CYP3A4 (0.72) | FGFR1SLC22A6ADORA2AADORA1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111606949-A | Preparation method of fosaprevir impurity | 浙江车头制药股份有限公司 | 2020-09-01 | — | — | CN | disclosed |