Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.67 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.56 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.56 |
| ▸ | PI4KA | P42356 | 1/20 | 0.56 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.56 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.56 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.56 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.55 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.55 |
| ▸ | AHCY | P23526 | 3/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.48 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.47 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.47 |
| ▸ | ADA | P00813 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27940881 | 0.88 | CYP3A4 (0.65) | CYP3A4ADORA2AADORA2BADORA1PI4KA | |
| SCHEMBL5030842 | 0.87 | CYP3A4 (0.64) | CYP3A4ADORA2AADORA2BADORA1PI4KA | |
| SCHEMBL5027395 | 0.86 | CYP3A4 (0.62) | CYP3A4ADORA2AADORA2BADORA1PI4KA | |
| SCHEMBL8897126 | 0.85 | CYP3A4 (0.61) | CYP3A4ADORA2AADORA2BADORA1PI4KA | |
| SCHEMBL6402722 | 0.85 | CYP3A4 (0.61) | CYP3A4ADORA2AADORA2BADORA1PI4KA | |
| SCHEMBL27653590 | 0.84 | ADORA2A (0.54) | CYP3A4ADORA2AADORA2BADORA1PI4KA | |
| SCHEMBL8895386 | 0.84 | CYP3A4 (0.60) | CYP3A4ADORA2AADORA2BADORA1PI4KA | |
| SCHEMBL17758842 | 0.83 | ADORA2A (0.51) | CYP3A4ADORA2AADORA2BADORA1PI4KA | |
| SCHEMBL28451287 | 0.83 | FGFR1 (0.59) | CYP3A4ADORA2AADORA2BADORA1PI4KA | |
| SCHEMBL27653606 | 0.82 | ADORA2A (0.50) | CYP3A4ADORA2AADORA2BADORA1PI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090176743-A1 | Methods for treating or preventing reactivation of a latent herpesvirus infection | BETH ISRAEL DEACONESS MEDICAL CENTER | 2009-07-09 | — | — | US | claimed |
| EP-1594507-A4 | NOVEL ANTIHERPES DRUG COMBINATIONS | UNIV MASSACHUSETTS (US) | 2008-10-01 | — | — | EP | claimed |
| WO-2007016450-A2 | METHODS FOR TREATING OR PREVENTING REACTIVATION OF A LATENT HERPESVIRUS INFECTION | BETH ISRAEL DEACONESS MEDICAL CENTER (US) | 2007-02-08 | — | — | WO | claimed |
| EP-1594507-A2 | NOVEL ANTIHERPES DRUG COMBINATIONS | The University of Massachussetts (US) | 2005-11-16 | — | — | EP | claimed |
| US-20040259832-A1 | Novel antiherpes drug combinations | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-12-23 | — | — | US | claimed |
| WO-2004069168-A2 | NOVEL ANTIHERPES DRUG COMBINATIONS | UNIVERSITY OF MASSACHUSETTS (US) | 2004-08-19 | — | — | WO | claimed |
| EP-2998307-B1 | PHOSPHORIC ACID/PHOSPHONIC ACID DERIVATIVES AND MEDICINAL USES THEREOF | BEIJING SL PHARMACEUTICAL CO LTD (CN) | 2018-10-31 | — | — | EP | disclosed |
| US-9932646-B2 | Detection and use of antiviral resistance mutations | ABL SA (LU) | 2018-04-03 | — | — | US | disclosed |
| US-9701982-B2 | Variants of hepatitis B virus with resistance to anti-viral nucleoside agents and applications thereof | ABL SA (LU) | 2017-07-11 | — | — | US | disclosed |
| US-9702005-B2 | Hepatitis B viral variants with reduced susceptibility to nucleoside analogs and uses thereof | ABL SA (LU) | 2017-07-11 | — | — | US | disclosed |
| US-9682109-B2 | Antiviral resistance mutants and applications thereof | ABL SA (LU) | 2017-06-20 | — | — | US | disclosed |
| US-20160115186-A1 | PHOSPHORIC ACID/PHOSPHONIC ACID DERIVATIVES AND MEDICINAL USES THEREOF | Nanjing Cavendish Bio-Engineering Technology Co., Ltd. (CN) | 2016-04-28 | — | — | US | disclosed |
| EP-2998307-A1 | PHOSPHORIC ACID/PHOSPHONIC ACID DERIVATIVES AND MEDICINAL USES THEREOF | Beijing Meibeita Drug Res Co., Ltd (CN) | 2016-03-23 | — | — | EP | disclosed |
| EP-1060182-A2 | NOVEL PRODRUGS FOR PHOSPHORUS-CONTAINING COMPOUNDS | Metabasis Therapeutics, Inc. (US) | 2000-12-20 | — | — | EP | disclosed |
| WO-1999045016-A9 | NOVEL PRODRUGS FOR PHOSPHORUS-CONTAINING COMPOUNDS | METABASIS THERAPEUTICS INC (US) | 2000-03-02 | — | — | WO | disclosed |
| WO-1999045016-A2 | NOVEL PRODRUGS FOR PHOSPHORUS-CONTAINING COMPOUNDS | METABASIS THERAPEUTICS, INC. (US) | 1999-09-10 | — | — | WO | disclosed |
| EP-0206459-B1 | 9-(PHOSPHONYLMETHOXYALKYL) ADENINES, METHOD FOR THEIR PREPARATION AND THEIR USE | Ceskoslovenska akademie ved (CS) | 1992-07-15 | — | — | EP | disclosed |
| EP-0253412-B1 | N-PHOSPHONYLMETHOXYALKYL DERIVATIVES OF PYRIMIDINE AND PURINE BASES, METHODS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREFROM WITH ANTIVIRAL ACTIVITY | Ceskoslovenska akademie ved (CS) | 1990-10-31 | — | — | EP | disclosed |
| US-4808716-A | VIRICIDES OR CHEMICAL INTERMEDIATES | CESKOSLOVENSKA AKADEMIC VED (CS) | 1989-02-28 | — | — | US | disclosed |
| EP-0206459-A2 | 9-(Phosphonylmethoxyalkyl) adenines, method for their preparation and their use | Ceskoslovenska akademie ved (CS) | 1986-12-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160115186-A1 | PHOSPHORIC ACID/PHOSPHONIC ACID DERIVATIVES AND MEDICINAL USES THEREOF | P2RY1, SQLE, PHOSPHO1 | CYP3A4 792/4885ADORA2A 151/4885ADORA2B 165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.