Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.54 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | XIAP | P98170 | 1/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
| ▸ | LAP3 | P28838 | 4/20 | 0.47 |
| ▸ | ANPEP | P15144 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9625571 | 1.00 | EPHX1 (0.54) | EPHX1SLC15A1SLC6A2TAAR1MAOA | |
| SCHEMBL9627376 | 1.00 | EPHX1 (0.54) | EPHX1SLC15A1SLC6A2TAAR1MAOA | |
| SCHEMBL9819869 | 1.00 | EPHX1 (0.54) | EPHX1SLC15A1SLC6A2TAAR1MAOA | |
| SCHEMBL1683172 | 1.00 | EPHX1 (0.54) | EPHX1SLC15A1SLC6A2TAAR1MAOA | |
| SCHEMBL6445044 | 0.82 | EPHX1 (0.58) | EPHX1SLC15A1SLC6A2TAAR1MAOA | |
| SCHEMBL6356479 | 0.82 | EPHX1 (0.58) | EPHX1SLC15A1SLC6A2TAAR1MAOA | |
| SCHEMBL6929688 | 0.82 | EPHX1 (0.58) | EPHX1SLC15A1SLC6A2TAAR1MAOA | |
| SCHEMBL7190709 | 0.82 | EPHX1 (0.58) | EPHX1SLC15A1SLC6A2TAAR1MAOA | |
| SCHEMBL22431194 | 0.82 | EPHX1 (0.58) | EPHX1SLC15A1SLC6A2TAAR1MAOA | |
| SCHEMBL9740410 | 0.82 | EPHX1 (0.58) | EPHX1SLC15A1SLC6A2TAAR1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5047400-A | Treatment of infection; antitumor agents | ADIR ET CIE (FR) | 1991-09-10 | — | — | US | claimed |
| EP-2235008-B1 | AMIDE COMPOUNDS AS BOOSTERS OF ANTIVIRALS | JANSSEN SCIENCES IRELAND UC (IE) | 2016-03-16 | — | — | EP | disclosed |
| EP-2235008-A2 | AMIDE COMPOUNDS AS BOOSTERS OF ANTIVIRALS | Tibotec Pharmaceuticals (IE) | 2010-10-06 | — | — | EP | disclosed |
| WO-2009071650-A2 | AMIDE COMPOUNDS AS BOOSTERS OF ANTIVIRALS | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2009-06-11 | — | — | WO | disclosed |
| EP-0346847-A2 | Amino acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1989-12-20 | — | — | EP | disclosed |