Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL779793 | 0.85 | P2RX7 (0.38) | P2RX7SSTR4MEN1KMT2AUSP2 | |
| SCHEMBL5847643 | 0.80 | SSTR4 (0.41) | SSTR4SMN1; SMN2GAATRPV1 | |
| SCHEMBL5847641 | 0.80 | SSTR4 (0.41) | SSTR4SMN1; SMN2GAATRPV1 | |
| SCHEMBL29948201 | 0.80 | SSTR4 (0.41) | SSTR4SMN1; SMN2GAATRPV1 | |
| SCHEMBL30207743 | 0.80 | SSTR4 (0.41) | SSTR4SMN1; SMN2GAATRPV1 | |
| SCHEMBL769058 | 0.80 | SSTR4 (0.41) | SSTR4SMN1; SMN2GAATRPV1 | |
| SCHEMBL24075070 | 0.79 | SSTR4 (0.40) | SSTR4SMN1; SMN2GAAMAP3K14TRPV1 | |
| SCHEMBL31276182 | 0.79 | SSTR4 (0.40) | SSTR4SMN1; SMN2GAAMAP3K14TRPV1 | |
| SCHEMBL22118222 | 0.79 | SSTR4 (0.40) | SSTR4SMN1; SMN2GAAMAP3K14TRPV1 | |
| SCHEMBL31085324 | 0.79 | ATM (0.47) | SSTR4SMN1; SMN2GAAMAP3K14TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111499619-B | Medicine for treating hepatic fibrosis and preparation method thereof | 温州医科大学附属第一医院 | 2021-05-18 | — | — | CN | disclosed |
| CN-111499619-A | Medicine for treating hepatic fibrosis and preparation method thereof | 温州医科大学附属第一医院 | 2020-08-07 | — | — | CN | disclosed |