Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29736073 | 0.89 | SIGMAR1 (0.45) | IDO1SIGMAR1KDM1AMAOAMAOB | |
| SCHEMBL546544 | 0.89 | SIGMAR1 (0.45) | IDO1SIGMAR1KDM1AMAOAMAOB | |
| Formaldehyde SCHEMBL27942062 | 0.88 | IDO1 (0.42) | IDO1SIGMAR1KDM1AMAOAMAOB | |
| Hydrochloric Acid SCHEMBL27471847 | 0.88 | SIGMAR1 (0.44) | IDO1SIGMAR1KDM1AMAOAMAOB | |
| Ammonia Solution, Strong SCHEMBL29163352 | 0.88 | SIGMAR1 (0.44) | IDO1SIGMAR1KDM1AMAOAMAOB | |
| SCHEMBL7326936 | 0.79 | KDM1A (0.42) | IDO1SIGMAR1KDM1AMAOAMAOB | |
| SCHEMBL10506304 | 0.78 | SIGMAR1 (0.40) | IDO1SIGMAR1MAOAMAOBKMT2A | |
| SCHEMBL29604657 | 0.76 | MAPT (0.38) | IDO1SIGMAR1KDM1AMAOAMAOB | |
| SCHEMBL6447320 | 0.75 | SIGMAR1 (0.43) | SIGMAR1KDM1AMAOAMAOBALDH1A1 | |
| Hydrochloric Acid SCHEMBL27611807 | 0.74 | SIGMAR1 (0.42) | SIGMAR1KDM1AMAOAMAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111499619-B | Medicine for treating hepatic fibrosis and preparation method thereof | 温州医科大学附属第一医院 | 2021-05-18 | — | — | CN | disclosed |
| CN-111499619-A | Medicine for treating hepatic fibrosis and preparation method thereof | 温州医科大学附属第一医院 | 2020-08-07 | — | — | CN | disclosed |