Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.37 |
| ▸ | OXTR | P30559 | 1/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 4/20 | 0.36 |
| ▸ | HTR2B | P41595 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | CASP7 | P55210 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28453362 | 0.88 | KMT2A (0.46) | MEN1KMT2AHTR2CHTR2BKDM4E | |
| SCHEMBL28898040 | 0.86 | MEN1 (0.39) | MEN1KMT2AAVPR2AVPR1AHTR2C | |
| SCHEMBL28451755 | 0.86 | MAPT (0.46) | MEN1KMT2AHTR2CHTR2BKDM4E | |
| SCHEMBL28457314 | 0.86 | GAA (0.41) | MEN1KMT2AHTR2CHTR2BKDM4E | |
| SCHEMBL28445944 | 0.86 | ALDH1A1 (0.46) | MEN1KMT2AAVPR2AVPR1AHTR2C | |
| SCHEMBL28452179 | 0.82 | KMT2A (0.37) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL28447937 | 0.82 | AR (0.38) | MEN1KMT2AHTR2CHTR2BKDM4E | |
| SCHEMBL28453210 | 0.82 | TSHR (0.43) | MEN1KMT2AHTR2CHTR2BKDM4E | |
| SCHEMBL28451766 | 0.80 | MEN1 (0.47) | MEN1KMT2AMAPTGAAHPGD | |
| SCHEMBL28448226 | 0.77 | ALDH1A1 (0.45) | MEN1KMT2AHTR2CHTR2BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110156789-B | Synthetic method of azacyclo-quinazoline compound | 东华理工大学 | 2020-09-04 | — | — | CN | disclosed |