Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MYB | P10242 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | GRK6 | P43250 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19328585 | 0.80 | EPHX1 (0.36) | MEN1KMT2ATSHR | |
| SCHEMBL19328562 | 0.80 | EPHX1 (0.36) | MEN1KMT2ATSHR | |
| SCHEMBL19328560 | 0.80 | EPHX1 (0.36) | MEN1KMT2ATSHR | |
| SCHEMBL19328583 | 0.80 | EPHX1 (0.36) | MEN1KMT2ATSHR | |
| SCHEMBL19328561 | 0.80 | EPHX1 (0.36) | MEN1KMT2ATSHR | |
| SCHEMBL19328570 | 0.79 | RET (0.37) | ALDH1A1CYP2A6MEN1KMT2AKDM4E | |
| SCHEMBL28453118 | 0.79 | TSHR (0.41) | ALDH1A1CYP2A6MYBCA2TSHR | |
| SCHEMBL19328624 | 0.79 | RET (0.37) | ALDH1A1CYP2A6MEN1KMT2AKDM4E | |
| SCHEMBL28453054 | 0.79 | EPHX1 (0.40) | KDM4EMAPTALOX15LMNA | |
| SCHEMBL19328572 | 0.79 | RET (0.37) | ALDH1A1CYP2A6MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109503454-B | Preparation method of indole compound | 北京化工大学 | 2020-09-04 | — | — | CN | disclosed |