Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.40 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.38 |
| ▸ | FADS1 | O60427 | 6/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19328560 | 0.80 | EPHX1 (0.36) | EPHX1CUL4A | |
| SCHEMBL19328561 | 0.80 | EPHX1 (0.36) | EPHX1CUL4A | |
| SCHEMBL19328562 | 0.80 | EPHX1 (0.36) | EPHX1CUL4A | |
| SCHEMBL19328583 | 0.80 | EPHX1 (0.36) | EPHX1CUL4A | |
| SCHEMBL19328624 | 0.79 | RET (0.37) | KDM4ELMNAMAPTALOX15 | |
| SCHEMBL28453023 | 0.79 | ALDH1A1 (0.38) | KDM4ELMNAMAPTALOX15 | |
| SCHEMBL19328570 | 0.79 | RET (0.37) | KDM4ELMNAMAPTALOX15 | |
| SCHEMBL28445267 | 0.79 | GAA (0.36) | KDM1AKDM4E | |
| SCHEMBL28453118 | 0.79 | TSHR (0.41) | — | |
| SCHEMBL19328623 | 0.79 | RET (0.37) | KDM4ELMNAMAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109503454-B | Preparation method of indole compound | 北京化工大学 | 2020-09-04 | — | — | CN | disclosed |