Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | PAK4 | O96013 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid Monomethyl Ester SCHEMBL29043734 | 0.95 | BRD4 (0.37) | BRD4CDC7JAK2ROCK2MAP4K4 | |
| SCHEMBL509851 | 0.93 | RAB9A (0.41) | BRD4CDC7JAK2ROCK2MAP4K4 | |
| SCHEMBL30025289 | 0.93 | RAB9A (0.41) | BRD4CDC7JAK2ROCK2MAP4K4 | |
| Methyl Phosphonate SCHEMBL28462465 | 0.88 | SMPD1 (0.42) | BRD4CDC7JAK2ROCK2MAP4K4 | |
| Manogepix SCHEMBL1323272 | 0.86 | NPC1 (0.37) | BRD4CDC7JAK2ROCK2MAP4K4 | |
| SCHEMBL30025372 | 0.86 | CDC7 (0.34) | BRD4CDC7JAK2ROCK2MAP4K4 | |
| SCHEMBL21054725 | 0.86 | CDC7 (0.34) | BRD4CDC7JAK2ROCK2MAP4K4 | |
| SCHEMBL21054935 | 0.85 | CDC7 (0.36) | BRD4CDC7JAK2ROCK2MAP4K4 | |
| SCHEMBL30025972 | 0.85 | JAK2 (0.36) | BRD4CDC7JAK2ROCK2MAP4K4 | |
| SCHEMBL30026137 | 0.85 | CDC7 (0.36) | BRD4CDC7JAK2ROCK2MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111698989-B | Heterocyclic substituted pyridine derivatives as antifungal agents | 安普利克斯制药公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-111698989-A | Heterocyclic substituted pyridine derivative antifungal agent | 安普利克斯制药公司 | 2020-09-22 | — | — | CN | disclosed |