Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA6 | P23280 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28453150 | 1.00 | STING1 (0.38) | STING1NR1H4EPHX2CA12CA1 | |
| SCHEMBL29080502 | 0.91 | STING1 (0.38) | STING1CNR2ALDH1A1LMNAHTT | |
| SCHEMBL20889072 | 0.91 | STING1 (0.45) | STING1ALDH1A1LMNAHTTL3MBTL1 | |
| SCHEMBL22313218 | 0.91 | STING1 (0.38) | STING1CNR2ALDH1A1LMNAHTT | |
| SCHEMBL29012734 | 0.91 | STING1 (0.45) | STING1ALDH1A1LMNAHTTL3MBTL1 | |
| SCHEMBL29406354 | 0.91 | STING1 (0.45) | STING1ALDH1A1LMNAHTTL3MBTL1 | |
| SCHEMBL28880366 | 0.83 | MAPT (0.42) | ALDH1A1LMNATPMTMAPTMEN1 | |
| SCHEMBL25098877 | 0.81 | STING1 (0.46) | STING1CA12CA1CA2CA9 | |
| SCHEMBL29868394 | 0.81 | STING1 (0.46) | STING1CA12CA1CA2CA9 | |
| SCHEMBL22519927 | 0.81 | DRD2 (0.41) | EPHX2CA1CA2ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113563313-B | Immunomodulator | 成都先导药物开发股份有限公司 | 2022-11-04 | — | — | CN | disclosed |
| CN-113563313-A | Immunomodulator | 成都先导药物开发股份有限公司 | 2021-10-29 | — | — | CN | disclosed |
| CN-111499617-B | Immunomodulator | 成都先导药物开发股份有限公司 | 2021-08-06 | — | — | CN | disclosed |
| CN-111499617-A | Immunomodulator | 成都先导药物开发股份有限公司 | 2020-08-07 | — | — | CN | disclosed |