Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28455080 | 0.95 | HPGD (0.39) | DHODHCNR1KMT2ACNR2HPGD | |
| SCHEMBL28455067 | 0.94 | POLB (0.39) | DHODHPOLBTHRBRECQLTDP1 | |
| SCHEMBL28447607 | 0.93 | CHIA (0.39) | DHODHPDE4BHSP90AA1CHIAHPGD | |
| SCHEMBL28451011 | 0.89 | HPGD (0.39) | DHODHPOLBTHRBRECQLTDP1 | |
| SCHEMBL28459476 | 0.89 | DHODH (0.38) | DHODH | |
| SCHEMBL24397793 | 0.87 | CHIA (0.39) | DHODHPDE4BCNR1CNR2CHIA | |
| SCHEMBL28458430 | 0.87 | DHODH (0.40) | DHODHPDE4BPDE4DPDE4APDE4C | |
| SCHEMBL28460675 | 0.87 | DHODH (0.34) | DHODHCNR1CNR2 | |
| SCHEMBL28456798 | 0.87 | DHODH (0.37) | DHODHPOLBRECQLL3MBTL1CNR1 | |
| SCHEMBL28461029 | 0.86 | DHODH (0.35) | DHODHL3MBTL1CNR1CNR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117285508-A | Preparation method of pyridyl pyrazole amide compound and intermediate thereof | 湖南化工研究院有限公司 | 2023-12-26 | — | — | CN | claimed |
| CN-117263908-A | Preparation of 1-pyridylpyrazole amide compound and intermediate thereof | 湖南化工研究院有限公司 | 2023-12-22 | — | — | CN | claimed |
| CN-116264894-A | Preparation and application of 1-pyridylpyrazole amide compound | 湖南化工研究院有限公司 | 2023-06-20 | — | — | CN | claimed |
| CN-114516855-A | Preparation of pyridylpyrazole amide compounds and intermediates therefor | 湖南化工研究院有限公司 | 2022-05-20 | — | — | CN | claimed |
| CN-114516854-A | Preparation method of 1-pyridyl pyrazole amide compound and intermediate thereof | 湖南化工研究院有限公司 | 2022-05-20 | — | — | CN | claimed |
| CN-111662269-B | 1-pyridyl pyrazole amide compound and preparation method and application thereof | 湖南化工研究院有限公司 | 2021-05-07 | — | — | CN | claimed |
| CN-111662269-A | 1-pyridyl pyrazole amide compound and preparation method and application thereof | 湖南化工研究院有限公司 | 2020-09-15 | — | — | CN | claimed |
| CN-116264894-B | Preparation and application of 1-pyridylpyrazole amide compound | 湖南化工研究院有限公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-117285508-A | Preparation method of pyridyl pyrazole amide compound and intermediate thereof | 湖南化工研究院有限公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-117263908-A | Preparation of 1-pyridylpyrazole amide compound and intermediate thereof | 湖南化工研究院有限公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-116264894-A | Preparation and application of 1-pyridylpyrazole amide compound | 湖南化工研究院有限公司 | 2023-06-20 | — | — | CN | disclosed |
| CN-114516855-A | Preparation of pyridylpyrazole amide compounds and intermediates therefor | 湖南化工研究院有限公司 | 2022-05-20 | — | — | CN | disclosed |
| CN-114516854-A | Preparation method of 1-pyridyl pyrazole amide compound and intermediate thereof | 湖南化工研究院有限公司 | 2022-05-20 | — | — | CN | disclosed |
| CN-111662269-B | 1-pyridyl pyrazole amide compound and preparation method and application thereof | 湖南化工研究院有限公司 | 2021-05-07 | — | — | CN | disclosed |
| CN-111662269-A | 1-pyridyl pyrazole amide compound and preparation method and application thereof | 湖南化工研究院有限公司 | 2020-09-15 | — | — | CN | disclosed |