Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 3/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28451756 | 0.95 | CHIA (0.36) | CHIADHODHPDE4BNTRK1 | |
| SCHEMBL28447607 | 0.94 | CHIA (0.39) | CHIADHODHPDE4BNTRK1LMNA | |
| SCHEMBL28458430 | 0.94 | DHODH (0.40) | CHIADHODHPDE4BNTRK1LMNA | |
| SCHEMBL28455067 | 0.93 | POLB (0.39) | DHODHPDE4BLMNACNR2SMN1; SMN2 | |
| SCHEMBL28451011 | 0.92 | HPGD (0.39) | DHODHCNR2HPGDALDH1A1P2RX7 | |
| SCHEMBL24397844 | 0.91 | CHIA (0.39) | CHIADHODHPDE4BNTRK1LMNA | |
| SCHEMBL24397959 | 0.90 | DHODH (0.39) | DHODHNTRK1 | |
| SCHEMBL28460725 | 0.88 | DHODH (0.38) | DHODHCNR2ALDH1A1SMN1; SMN2CNR1 | |
| SCHEMBL28451020 | 0.88 | DHODH (0.38) | DHODHLMNACNR2HPGDALDH1A1 | |
| SCHEMBL24397881 | 0.88 | DHODH (0.35) | DHODHCNR2ALDH1A1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116264894-B | Preparation and application of 1-pyridylpyrazole amide compound | 湖南化工研究院有限公司 | 2024-07-09 | — | — | CN | claimed |
| CN-117546858-A | Insecticidal composition for preventing and controlling lepidoptera, hemiptera and thysanoptera pests and application thereof | 湖南化工研究院有限公司 | 2024-02-13 | — | — | CN | claimed |
| CN-117285508-A | Preparation method of pyridyl pyrazole amide compound and intermediate thereof | 湖南化工研究院有限公司 | 2023-12-26 | — | — | CN | claimed |
| CN-117263908-A | Preparation of 1-pyridylpyrazole amide compound and intermediate thereof | 湖南化工研究院有限公司 | 2023-12-22 | — | — | CN | claimed |
| CN-116264894-A | Preparation and application of 1-pyridylpyrazole amide compound | 湖南化工研究院有限公司 | 2023-06-20 | — | — | CN | claimed |
| CN-114516855-A | Preparation of pyridylpyrazole amide compounds and intermediates therefor | 湖南化工研究院有限公司 | 2022-05-20 | — | — | CN | claimed |
| CN-114516854-A | Preparation method of 1-pyridyl pyrazole amide compound and intermediate thereof | 湖南化工研究院有限公司 | 2022-05-20 | — | — | CN | claimed |
| CN-111662269-B | 1-pyridyl pyrazole amide compound and preparation method and application thereof | 湖南化工研究院有限公司 | 2021-05-07 | — | — | CN | claimed |
| CN-111662269-A | 1-pyridyl pyrazole amide compound and preparation method and application thereof | 湖南化工研究院有限公司 | 2020-09-15 | — | — | CN | claimed |
| CN-116264894-B | Preparation and application of 1-pyridylpyrazole amide compound | 湖南化工研究院有限公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-117546858-A | Insecticidal composition for preventing and controlling lepidoptera, hemiptera and thysanoptera pests and application thereof | 湖南化工研究院有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-117285508-A | Preparation method of pyridyl pyrazole amide compound and intermediate thereof | 湖南化工研究院有限公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-117263908-A | Preparation of 1-pyridylpyrazole amide compound and intermediate thereof | 湖南化工研究院有限公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-116264894-A | Preparation and application of 1-pyridylpyrazole amide compound | 湖南化工研究院有限公司 | 2023-06-20 | — | — | CN | disclosed |
| CN-114516855-A | Preparation of pyridylpyrazole amide compounds and intermediates therefor | 湖南化工研究院有限公司 | 2022-05-20 | — | — | CN | disclosed |
| CN-114516854-A | Preparation method of 1-pyridyl pyrazole amide compound and intermediate thereof | 湖南化工研究院有限公司 | 2022-05-20 | — | — | CN | disclosed |
| US-20220132846-A1 | 1-PYRIDYL-PYRAZOLYL AMIDE COMPOUNDS AND PREPARATION AND USES THEREOF | HUNAN RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD. (CN) | 2022-05-05 | — | — | US | disclosed |
| CN-111662269-B | 1-pyridyl pyrazole amide compound and preparation method and application thereof | 湖南化工研究院有限公司 | 2021-05-07 | — | — | CN | disclosed |
| CN-111662269-A | 1-pyridyl pyrazole amide compound and preparation method and application thereof | 湖南化工研究院有限公司 | 2020-09-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220132846-A1 | 1-PYRIDYL-PYRAZOLYL AMIDE COMPOUNDS AND PREPARATION AND USES THEREOF | ACHE, PDHB, PDXK | CHIA 1680/4885DHODH 1362/4885PDE4B 46/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.