Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 5/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 4/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22288334 | 1.00 | TDP1 (0.43) | TDP1MEN1GAAKMT2ACA2 | |
| SCHEMBL18262010 | 0.90 | TDP1 (0.50) | TDP1MEN1GAAKMT2ACA2 | |
| SCHEMBL18487257 | 0.90 | TDP1 (0.50) | TDP1MEN1GAAKMT2ACA2 | |
| SCHEMBL18262007 | 0.90 | TDP1 (0.50) | TDP1MEN1GAAKMT2ACA2 | |
| SCHEMBL13092290 | 0.83 | TDP1 (0.44) | TDP1MEN1GAAKMT2ACA2 | |
| SCHEMBL20437999 | 0.83 | TDP1 (0.44) | TDP1MEN1GAAKMT2ACA2 | |
| SCHEMBL19420087 | 0.83 | TDP1 (0.44) | TDP1MEN1GAAKMT2ACA2 | |
| SCHEMBL7131446 | 0.83 | TDP1 (0.44) | TDP1MEN1GAAKMT2ACA2 | |
| SCHEMBL661593 | 0.83 | TDP1 (0.49) | TDP1MEN1GAAKMT2ACA2 | |
| SCHEMBL18262802 | 0.83 | MEN1 (0.46) | TDP1MEN1GAAKMT2ACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111499617-A | Immunomodulator | 成都先导药物开发股份有限公司 | 2020-08-07 | — | — | CN | disclosed |