Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.50 |
| ▸ | ACE | P12821 | 2/20 | 0.45 |
| ▸ | ECE1 | P42892 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL28193040 | 0.89 | ACE (0.41) | ITGB3ITGA2BACETYRCTSL | |
| SCHEMBL5613893 | 0.88 | ACE (0.51) | ITGB3ITGA2BACEECE1DPP8 | |
| SCHEMBL31190266 | 0.88 | ACE (0.51) | ITGB3ITGA2BACEECE1DPP8 | |
| SCHEMBL2157075 | 0.88 | ACE (0.51) | ITGB3ITGA2BACEECE1DPP8 | |
| SCHEMBL30758311 | 0.88 | TYR (0.49) | ITGB3ITGA2BACEECE1TYR | |
| SCHEMBL8579349 | 0.88 | TYR (0.49) | ITGB3ITGA2BACEECE1TYR | |
| SCHEMBL8579351 | 0.88 | TYR (0.49) | ITGB3ITGA2BACEECE1TYR | |
| SCHEMBL22804041 | 0.88 | TYR (0.49) | ITGB3ITGA2BACEECE1TYR | |
| Hydrochloric Acid SCHEMBL31235655 | 0.88 | ACE (0.50) | ITGB3ITGA2BACEECE1DPP8 | |
| Hydrochloric Acid SCHEMBL28030248 | 0.88 | ACE (0.50) | ITGB3ITGA2BACEECE1DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111686815-B | Self-assembled nano material and preparation method and application thereof | 北京化工大学 | 2023-07-14 | — | — | CN | disclosed |
| CN-111686815-A | Self-assembly nano material and preparation method and application thereof | 北京化工大学 | 2020-09-22 | — | — | CN | disclosed |