Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F12 | P00748 | 15/20 | 0.40 |
| ▸ | F2 | P00734 | 9/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22492312 | 0.86 | F12 (0.39) | F12F2NPC1RAB9A | |
| SCHEMBL22492323 | 0.76 | RAD52 (0.43) | F12F2KMT2AMAPK1GAA | |
| SCHEMBL22492410 | 0.74 | CYP2C19 (0.44) | NPC1RAB9AKMT2AGAA | |
| SCHEMBL4985526 | 0.72 | NPC1 (0.40) | F12F2NPC1RAB9AKMT2A | |
| SCHEMBL17232737 | 0.71 | CYP2C9 (0.34) | F12F2NPC1RAB9AKMT2A | |
| SCHEMBL23340392 | 0.70 | NPC1 (0.36) | F12F2NPC1RAB9AKMT2A | |
| SCHEMBL21385783 | 0.70 | HSD17B10 (0.34) | F12F2NPC1RAB9AKMT2A | |
| SCHEMBL28460855 | 0.69 | P2RX7 (0.31) | F12 | |
| SCHEMBL3461277 | 0.69 | BRD4 (0.41) | NPC1RAB9AKMT2AGAANPSR1 | |
| SCHEMBL5072632 | 0.68 | MAPT (0.43) | F12F2NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111670034-A | Pyranopyrazoles and pyrazolopyridines immunomodulators for the treatment of autoimmune diseases | 洛克菲勒大学 | 2020-09-15 | — | — | CN | disclosed |