Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.75 |
| ▸ | PKM | P14618 | 2/20 | 0.75 |
| ▸ | MEN1 | O00255 | 2/20 | 0.75 |
| ▸ | USP2 | O75604 | 1/20 | 0.75 |
| ▸ | HTR3A | P46098 | 4/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.52 |
| ▸ | HTR3B | O95264 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.52 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.52 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28538954 | 0.87 | KDM4E (0.98) | KDM4EALDH1A1KMT2APKMMEN1 | |
| SCHEMBL3551338 | 0.86 | PKM (0.75) | KDM4EALDH1A1KMT2APKMMEN1 | |
| Ethane SCHEMBL6102425 | 0.84 | KDM4E (0.73) | KDM4EALDH1A1KMT2APKMMEN1 | |
| SCHEMBL28462273 | 0.83 | KDM4E (0.73) | KDM4EALDH1A1KMT2APKMMEN1 | |
| SCHEMBL16832477 | 0.83 | PKM (1.00) | KDM4EALDH1A1KMT2APKMMEN1 | |
| SCHEMBL4007192 | 0.82 | NPC1 (0.58) | KDM4EALDH1A1KMT2APKMMEN1 | |
| SCHEMBL30604110 | 0.81 | PKM (0.68) | KDM4EALDH1A1KMT2APKMMEN1 | |
| SCHEMBL5910624 | 0.80 | KMT2A (0.69) | KDM4EALDH1A1KMT2APKMMEN1 | |
| SCHEMBL15521623 | 0.80 | DHODH (0.78) | KDM4EALDH1A1KMT2APOLBHPGD | |
| SCHEMBL5910282 | 0.80 | KMT2A (1.00) | KDM4EALDH1A1KMT2APKMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111574530-B | ACC inhibitor and medical application thereof | 徐州医科大学 | 2022-07-26 | — | — | CN | disclosed |
| CN-111925357-A | Acylhydrazone compound, pharmaceutical composition and application thereof | 中国科学院昆明植物研究所 | 2020-11-13 | — | — | CN | disclosed |
| CN-111574530-A | ACC inhibitor and medical application thereof | 徐州医科大学 | 2020-08-25 | — | — | CN | disclosed |