Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 2/20 | 0.47 |
| ▸ | CES1 | P23141 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8383210 | 1.00 | PRSS1 (0.50) | PRSS1PRSS2PRSS3CES2CES1 | |
| SCHEMBL1133494 | 1.00 | PRSS1 (0.50) | PRSS1PRSS2PRSS3CES2CES1 | |
| SCHEMBL9997625 | 1.00 | PRSS1 (0.50) | PRSS1PRSS2PRSS3CES2CES1 | |
| SCHEMBL962498 | 0.98 | PRSS1 (0.48) | PRSS1PRSS2PRSS3CES2CES1 | |
| SCHEMBL14866985 | 0.97 | PRSS1 (0.52) | PRSS1PRSS2PRSS3CES2CES1 | |
| SCHEMBL15155157 | 0.97 | PRSS1 (0.52) | PRSS1PRSS2PRSS3CES2CES1 | |
| SCHEMBL14866986 | 0.97 | PRSS1 (0.52) | PRSS1PRSS2PRSS3CES2CES1 | |
| SCHEMBL965455 | 0.94 | KMT2A (0.49) | PRSS1PRSS2PRSS3CES2CES1 | |
| SCHEMBL966669 | 0.90 | TSHR (0.55) | CES2CES1KMT2AMEN1NPC1 | |
| SCHEMBL14159304 | 0.89 | PRSS1 (0.55) | PRSS1PRSS2PRSS3CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113646052-B | Reversible thermochromic composition, reversible thermochromic microcapsule pigment, and writing instrument | 百乐墨水株式会社 | 2024-05-17 | — | — | CN | disclosed |
| CN-110446770-B | Reversible thermochromic composition and reversible thermochromic microcapsule pigment containing the same | 百乐墨水株式会社 | 2023-08-08 | — | — | CN | disclosed |
| CN-115449262-A | Marking composition | 桑福德有限合伙人公司 | 2022-12-09 | — | — | CN | disclosed |
| CN-111263795-B | Reversible thermal discoloration aqueous ink composition and writing instrument using the same | 株式会社百乐 | 2022-05-03 | — | — | CN | disclosed |
| CN-113785023-A | Water-based ink composition for reversible thermal discoloration writing instrument, refill containing the same, and water-based ballpoint pen | 株式会社百乐 | 2021-12-10 | — | — | CN | disclosed |
| CN-113646052-A | Reversible thermal discoloration composition, reversible thermal discoloration microcapsule pigment encapsulating the reversible thermal discoloration composition, and writing instrument using the reversible thermal discoloration microcapsule pigment | 百乐墨水株式会社 | 2021-11-12 | — | — | CN | disclosed |
| CN-111263795-A | Reversible thermal discoloration aqueous ink composition and writing instrument using the same | 株式会社百乐 | 2020-06-09 | — | — | CN | disclosed |