Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 3/20 | 0.46 |
| ▸ | CES1 | P23141 | 3/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | CTSG | P08311 | 1/20 | 0.43 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1133494 | 0.98 | PRSS1 (0.50) | PRSS1PRSS2PRSS3KMT2AMEN1 | |
| SCHEMBL9997625 | 0.98 | PRSS1 (0.50) | PRSS1PRSS2PRSS3KMT2AMEN1 | |
| SCHEMBL28455282 | 0.98 | PRSS1 (0.50) | PRSS1PRSS2PRSS3KMT2AMEN1 | |
| SCHEMBL8383210 | 0.98 | PRSS1 (0.50) | PRSS1PRSS2PRSS3KMT2AMEN1 | |
| SCHEMBL965455 | 0.95 | KMT2A (0.49) | PRSS1PRSS2PRSS3KMT2AMEN1 | |
| SCHEMBL14866985 | 0.95 | PRSS1 (0.52) | PRSS1PRSS2PRSS3KMT2AMEN1 | |
| SCHEMBL15155157 | 0.95 | PRSS1 (0.52) | PRSS1PRSS2PRSS3KMT2AMEN1 | |
| SCHEMBL14866986 | 0.95 | PRSS1 (0.52) | PRSS1PRSS2PRSS3KMT2AMEN1 | |
| SCHEMBL966669 | 0.92 | TSHR (0.55) | KMT2AMEN1NPC1TSHRCES2 | |
| SCHEMBL14159304 | 0.90 | PRSS1 (0.55) | PRSS1PRSS2PRSS3KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260062580-A1 | REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT | THE PILOT INK CO., LTD. (JP) | 2026-03-05 | — | — | US | disclosed |
| EP-3954745-B1 | REVERSIBLY THERMOCHROMIC AQUEOUS INK COMPOSITION FOR WRITING UTENSILS, AND REFILL AND WATER-BASED BALLPOINT PEN EACH INTERNALLY CONTAINING SAME | KK PILOT CORPORATION ALSO TRADING AS PILOT CORPORATION (JP) | 2026-01-07 | — | — | EP | disclosed |
| US-12460099-B2 | Reversibly thermochromic composition, reversibly thermochromic microcapsule pigment encapsulating reversibly thermochromic composition, and writing instrument using reversibly thermochromic microcapsule pigment | THE PILOT INK CO., LTD. (JP) | 2025-11-04 | — | — | US | disclosed |
| US-12421411-B2 | Aqueous ink composition for reversibly thermochromic writing instrument, and refill and aqueous ballpoint pen incorporating aqueous ink composition for reversibly thermochromic writing instrument | KABUSHIKI KAISHA PILOT CORPORATION (JP) | 2025-09-23 | — | — | US | disclosed |
| CN-115710637-B | Extractant and application thereof in extraction of lithium, rubidium and cesium | 中国科学院过程工程研究所 | 2025-03-11 | — | — | CN | disclosed |
| EP-3608386-B1 | REVERSIBLY THERMOCHROMIC COMPOSITION, AND REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT HAVING SAME ENCLOSED THEREIN | PILOT INK CO LTD (JP) | 2025-02-19 | — | — | EP | disclosed |
| US-12123107-B2 | Reversibly thermochromic composite fiber | KABUSHIKI KAISHA PILOT CORPORATION (JP) | 2024-10-22 | — | — | US | disclosed |
| US-12011943-B2 | Image forming apparatus | TOSHIBA TEC KABUSHIKI KAISHA (JP) | 2024-06-18 | — | — | US | disclosed |
| EP-3702419-B1 | REVERSIBLE THERMOCHROMIC AQUEOUS INK COMPOSITION AND WRITING INSTRUMENT USING SAME | KK PILOT CORPORATION ALSO TRADING AS PILOT CORPORATION (JP) | 2023-09-20 | — | — | EP | disclosed |
| CN-110446770-B | Reversible thermochromic composition and reversible thermochromic microcapsule pigment containing the same | 百乐墨水株式会社 | 2023-08-08 | — | — | CN | disclosed |
| EP-0908501-A1 | Reversible thermochromic composition | THE PILOT INK CO., LTD. (JP) | 1999-04-14 | — | — | EP | disclosed |
| EP-0873881-A1 | Reversible thermochromic compositions | The Pilot Ink CO., Ltd. (JP) | 1998-10-28 | — | — | EP | disclosed |
| EP-0665119-B1 | Thermochromic colour-memory composition | PILOT INK CO LTD (JP) | 1997-12-03 | — | — | EP | disclosed |
| US-5558699-A | COLOR IS RETAINED AFTER HEATING OR COOLING IS WITHDRAWN, REACTION MEDIUM IS ALKYL OR ALKYLARYL KETONE | THE PILOT INK CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |
| EP-0440762-B1 | 5-OXY-2-PHENYLPYRIDINES AND LIQUID-CRYSTAL MATERIALS | HOECHST AG (DE) | 1996-07-17 | — | — | EP | disclosed |
| EP-0665119-A1 | Thermochromic colour-memory composition | THE PILOT INK CO., LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |
| US-5196141-A | Electrooptical display | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-03-23 | — | — | US | disclosed |
| EP-0440762-A1 | 5-OXY-2-PHENYLPYRIDINES AND LIQUID-CRYSTAL MATERIALS. | MERCK PATENT GMBH (DE) | 1991-08-14 | — | — | EP | disclosed |
| WO-1991002722-A1 | 5-OXY-2-PHENYLPYRIDINES AND LIQUID-CRYSTAL MATERIALS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-03-07 | — | — | WO | disclosed |
| US-4336397-A | 2,4-Dioxo-4-substituted-1-butanoic acid derivatives useful in treating urinary tract calcium oxalate lithiasis | MERCK & CO., INC. (US) | 1982-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260062580-A1 | REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT | TYR, SCO2, HBB | PRSS1 4480/4885PRSS2 3393/4885PRSS3 3567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.