Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 20/20 | 0.65 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.65 |
| ▸ | RORA | P35398 | 1/20 | 0.65 |
| ▸ | RORB | Q92753 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28455348 | 0.90 | RORC (0.67) | RORCNR1I2RORARORB | |
| SCHEMBL24840409 | 0.82 | RORC (0.83) | RORCNR1I2RORARORB | |
| SCHEMBL28979128 | 0.82 | RORC (0.83) | RORCNR1I2RORARORB | |
| SCHEMBL30110872 | 0.82 | RORC (0.83) | RORCNR1I2RORARORB | |
| SCHEMBL24839974 | 0.81 | RORC (0.67) | RORCNR1I2RORARORB | |
| SCHEMBL24839973 | 0.80 | RORC (0.58) | RORCNR1I2RORARORB | |
| SCHEMBL21312626 | 0.80 | RORC (0.85) | RORCNR1I2RORARORB | |
| Cintirorgon SCHEMBL20957370 | 0.79 | RORC (1.00) | RORCNR1I2RORARORB | |
| Cintirorgon SCHEMBL18302870 | 0.79 | RORC (1.00) | RORCNR1I2RORARORB | |
| Cintirorgon SCHEMBL29379832 | 0.79 | RORC (1.00) | RORCNR1I2RORARORB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111499591-A | ROR gamma modulators | 山东轩竹医药科技有限公司 | 2020-08-07 | — | — | CN | disclosed |