Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 6/20 | 0.67 |
| ▸ | CKS1B | P61024 | 5/20 | 0.55 |
| ▸ | SKP2 | Q13309 | 5/20 | 0.55 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28402292 | 0.90 | NAMPT (0.60) | SLC22A12CKS1BSKP2NAMPTPIK3CA | |
| SCHEMBL28450035 | 0.88 | SLC22A12 (0.74) | SLC22A12CKS1BSKP2PIK3CAPTGES2 | |
| SCHEMBL28449527 | 0.83 | SLC22A12 (0.72) | SLC22A12PIK3CAALDH1A1 | |
| SCHEMBL28450046 | 0.81 | SLC22A12 (0.68) | SLC22A12CKS1BSKP2PTGS2 | |
| SCHEMBL28449528 | 0.80 | SLC22A12 (1.00) | SLC22A12PTGES2 | |
| SCHEMBL28448184 | 0.80 | SLC22A12 (0.69) | SLC22A12CKS1BSKP2PTGES2 | |
| SCHEMBL28449525 | 0.80 | SLC22A12 (0.67) | SLC22A12CKS1BSKP2 | |
| SCHEMBL28452095 | 0.80 | SLC22A12 (0.74) | SLC22A12CKS1BSKP2PTGES2 | |
| SCHEMBL6691608 | 0.79 | MEN1 (0.52) | SLC22A12CKS1BSKP2NAMPTPTGS2 | |
| SCHEMBL28445603 | 0.78 | SLC22A12 (0.55) | SLC22A12CKS1BSKP2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106831556-B | Sulfonamide compound, preparation method thereof and application of sulfonamide compound as urate transporter inhibitor medicine | 成都海创药业有限公司 | 2020-09-01 | — | — | CN | disclosed |