SCHEMBL28402292

SCHEMBL28402292

O=S(=O)(Nc1ccccc1-c1cccnc1)c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAMPT P43490 1/20 0.60
MCOLN3 Q8TDD5 2/20 0.58
CA12 O43570 1/20 0.58
CA2 P00918 1/20 0.58
LMNA P02545 1/20 0.58
CA9 Q16790 1/20 0.58
CKS1B P61024 4/20 0.56
SKP2 Q13309 4/20 0.56
SLC22A12 Q96S37 2/20 0.54
PTGS2 P35354 2/20 0.51
ALDH1A1 P00352 2/20 0.51
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
PIK3CA P42336 1/20 0.51
GLO1 Q04760 2/20 0.50
SLC40A1 Q9NP59 2/20 0.50
G6PD P11413 1/20 0.50
NFKBIA P25963 1/20 0.50
AGTR1 P30556 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28455396 0.90 SLC22A12 (0.67) NAMPTCKS1BSKP2SLC22A12PTGS2
SCHEMBL23057275 0.86 NAMPT (0.53) NAMPTMCOLN3CA12CA2LMNA
SCHEMBL29979013 0.86 NAMPT (0.53) NAMPTMCOLN3CA12CA2LMNA
SCHEMBL5410713 0.84 MCOLN3 (0.78) MCOLN3CA12CA2LMNACA9
SCHEMBL6691608 0.80 MEN1 (0.52) NAMPTCA12CA2CA9CKS1B
SCHEMBL29264214 0.79 NAMPT (0.50) NAMPTCKS1BSKP2SLC22A12ALDH1A1
SCHEMBL28450035 0.78 SLC22A12 (0.74) MCOLN3CA12CA2LMNACA9
SCHEMBL8657373 0.77 LMNA (0.63) MCOLN3CA12CA2LMNACA9
SCHEMBL8629748 0.77 PIK3CA (0.52) NAMPTCKS1BSKP2SLC22A12PTGS2
SCHEMBL165615 0.77 NAMPT (1.00) NAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108822002-B Method for synthesizing N-aryl sulfonamide under assistance of ultrasonic waves 中南大学 2020-05-05 CN disclosed