Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3302772 | 0.77 | TP53 (0.65) | TP53TDP1NPC1CASP3SENP8 | |
| SCHEMBL2464276 | 0.76 | MAPT (0.44) | MAPTGAAALDH1A1HSD17B10PDPK1 | |
| SCHEMBL27704551 | 0.74 | TP53 (0.43) | TP53TDP1NPC1CASP3SENP8 | |
| SCHEMBL6704634 | 0.74 | PDPK1 (0.44) | PDPK1FBP1 | |
| SCHEMBL559603 | 0.72 | GRIN2D (0.45) | MAPTKDM4EGAAALDH1A1POLB | |
| SCHEMBL3298140 | 0.71 | TP53 (0.58) | TP53TDP1NPC1CASP3SENP8 | |
| SCHEMBL18240768 | 0.70 | TP53 (0.56) | TP53TDP1NPC1CASP3SENP8 | |
| SCHEMBL2357901 | 0.70 | TP53 (0.56) | TP53TDP1NPC1CASP3SENP8 | |
| SCHEMBL21847980 | 0.68 | PTGS1 (0.69) | TP53TDP1NPC1CASP3SENP8 | |
| SCHEMBL1795132 | 0.68 | PTGS1 (0.69) | TP53TDP1NPC1CASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111556872-A | Synthesis of boronic ester derivatives and uses thereof | 梅琳塔治疗公司 | 2020-08-18 | — | — | CN | disclosed |