Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 3/20 | 0.38 |
| ▸ | RET | P07949 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2464276 | 0.82 | MAPT (0.44) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL2464131 | 0.81 | MAPT (0.52) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL2464133 | 0.81 | MAPT (0.52) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL10141196 | 0.77 | — | — | |
| SCHEMBL6159482 | 0.77 | — | — | |
| SCHEMBL19596 | 0.77 | — | — | |
| SCHEMBL10141206 | 0.77 | — | — | |
| SCHEMBL3813193 | 0.77 | — | — | |
| SCHEMBL22163881 | 0.77 | — | — | |
| SCHEMBL149121 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2129656-B1 | ADAMANTANE-DIPYRROMETHANE DERIVATIVES, METHOD OF PREPARATION AND APPLICATIONS IN ANION SENSING | RUDER BOSKOVIC INST (HR) | 2013-12-04 | — | — | EP | disclosed |
| EP-2193172-B1 | PHENYLPYRIDO [1,2-A]INDOLIUM-DERIVED THIOL/DISULFIDE DYE, DYE COMPOSITION COMPRISING THIS DYE, PROCESS FOR LIGHTENING KERATIN MATERIALS USING THIS DYE | OREAL (FR) | 2013-05-01 | — | — | EP | disclosed |
| US-8420684-B2 | imidazole derivatives; Alzheimer's Disease, Down syndrome, Huntington's Disease; hypotensive agents; sleeping/eating disorders, anxiolytic agents, antidepressants, antiepileptic agents; drug abuse/withdrawl; 4-Cyclopropylimino-5-(3,4-dihydro-2H-pyran-2-yl)-1-(3-imidazol-1-yl-propyl)-imidazolidin-2-one | PROBIODRUG AG (DE) | 2013-04-16 | — | — | US | disclosed |
| US-8398722-B2 | Phenylpyrido [1,2-A] indolium-derived thiol/disulfide dye, dye composition comprising this dye, process for lightening keratin materials using this dye | L'OREAL (FR) | 2013-03-19 | — | — | US | disclosed |
| US-20120266392-A1 | PHENYLPYRIDO [1,2-A] INDOLIUM-DERIVED THIOL/DISULFIDE DYE, DYE COMPOSITION COMPRISING THIS DYE, PROCESS FOR LIGHTENING KERATIN MATERIALS USING THIS DYE | L'OREAL (FR) | 2012-10-25 | — | — | US | disclosed |
| US-20120031422-A9 | FLUORESCENT ENTITY, DYEING COMPOSITION CONTAINING AT LEAST ONE FLUORESCENT ENTITY COMPRISING AT LEAST ONE HETEROCYCLE, WITH AT LEAST ONE INTERNAL CATIONIC CHARGE, AND METHOD FOR LIGHTENING KERATIN MATERIALS USING SAID AT LEAST ONE FLUORESCENT ENTITY | L'OREAL S.A. (FR) | 2012-02-09 | — | — | US | disclosed |
| US-8038732-B2 | Fluorescent entity, dyeing composition containing at least one fluorescent entity, and method for lightening keratin materials using said at least one fluorescent entity | L'OREAL S.A. (FR) | 2011-10-18 | — | — | US | disclosed |
| US-8034125-B2 | Dye composition comprising at least one colorless disulfide/thiol precursor, and dyeing process using the composition | L'OREAL S.A. (FR) | 2011-10-11 | — | — | US | disclosed |
| US-8022097-B2 | Adamantane-dipyrromethane derivatives, method of preparation and applications in anion sensing | RUDJER BOSKOVIC INSTITUTE (HR) | 2011-09-20 | — | — | US | disclosed |
| EP-2205681-B1 | DYE COMPOSITION COMPRISING AT LEAST ONE COLORLESS DISULFIDE/THIOL PRECURSOR, AND DYEING PROCESS USING THE COMPOSITION | OREAL (FR) | 2011-08-31 | — | — | EP | disclosed |
| US-20090172897-A1 | STYRYL THIOL/DISULFIDE COMPOUND WITH A HYDROXY(CYCLO)ALKYLAMINO UNIT, PROCESS FOR LIGHTENING KERATIN MATERIALS USING SAME | L'OREAL S.A. (FR) | 2009-07-09 | — | — | US | disclosed |
| US-20090126125-A1 | STYRYL TETRAHYDROQUINOLINIUM THIOL/DISULFIDE DYE COMPOUND AND METHOD FOR LIGHTENING KERATIN MATERIALS USING THE SAME | L'OREAL S.A. (FR) | 2009-05-21 | — | — | US | disclosed |
| WO-2009040354-A1 | DYE COMPOSITION COMPRISING AT LEAST ONE COLORLESS DISULFIDE/THIOL PRECURSOR, AND DYEING PROCESS USING THE COMPOSITION | L'OREAL (FR) | 2009-04-02 | — | — | WO | disclosed |
| WO-2009037348-A1 | INDOLINIUM-DERIVED THIOL/DISULFIDE DYE, DYE COMPOSITION COMPRISNG THIS DYE, PROCESS FOR LIGHTENING KERATIN MATERIALS USING THIS DYE | L'OREAL (FR) | 2009-03-26 | — | — | WO | disclosed |
| WO-2009037350-A2 | DIKETOPYRROLO[3,4-c]PYRROLE THIOL/DISULFIDE DYE, COMPOSITION COMPRISING THIS DYE, PROCESS FOR LIGHTENING KERATIN MATERIALS USING THIS DYE | L'OREAL (FR) | 2009-03-26 | — | — | WO | disclosed |
| WO-2009037325-A2 | THIOL/DISULFIDE INDOLE-DERIVED, STYRYL DYE, DYE COMPOSITION COMPRISING SAID DYE, PROCESS FOR LIGHTENING KERATIN MATERIALS USING THIS DYE | L'OREAL (FR) | 2009-03-26 | — | — | WO | disclosed |
| WO-2009037324-A2 | PHENYLPYRIDO [1,2-A] INDOLIUM-DERIVED THIOL/DISULFIDE DYE, DYE COMPOSITION COMPRISING THIS DYE, PROCESS FOR LIGHTENING KERATIN MATERIALS USING THIS DYE | L'OREAL (FR) | 2009-03-26 | — | — | WO | disclosed |
| WO-2008114067-A1 | ADAMANTANE-DIPYRROMETHANE DERIVATIVES, METHOD OF PREPARATION AND APPLICATIONS IN ANION SENSING | RUDER BOSKOVIC INSTITUTE (HR) | 2008-09-25 | — | — | WO | disclosed |
| US-20080221086-A1 | Novel Inhibitors of Glutaminyl Cyclase | PROBIODRUG AG (DE) | 2008-09-11 | — | — | US | disclosed |
| WO-2008055947-A1 | NOVEL INHIBITORS OF GLUTAMINYL CYCLASE | PROBIODRUG AG (DE) | 2008-05-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120031422-A9 | FLUORESCENT ENTITY, DYEING COMPOSITION CONTAINING AT LEAST ONE FLUORESCENT ENTITY COMPRISING AT LEAST ONE HETEROCYCLE, WITH AT LEAST ONE INTERNAL CATIONIC CHARGE, AND METHOD FOR LIGHTENING KERATIN MATERIALS USING SAID AT LEAST ONE FLUORESCENT ENTITY | KRT18, KRTCAP2, DSG1 | GRIN2D 3807/4885GRIN3B 4022/4885GRIN1 3283/4885 |
| US-20090126125-A1 | STYRYL TETRAHYDROQUINOLINIUM THIOL/DISULFIDE DYE COMPOUND AND METHOD FOR LIGHTENING KERATIN MATERIALS USING THE SAME | KRT18, TST, CYBA | GRIN2D 1586/4885GRIN3B 1396/4885GRIN1 1653/4885 |
| US-20080221086-A1 | Novel Inhibitors of Glutaminyl Cyclase | GLS, GLS2, GLUL | GRIN2D 1071/4885GRIN3B 852/4885GRIN1 295/4885 |
| US-20090172897-A1 | STYRYL THIOL/DISULFIDE COMPOUND WITH A HYDROXY(CYCLO)ALKYLAMINO UNIT, PROCESS FOR LIGHTENING KERATIN MATERIALS USING SAME | KRT18, TST, CYBA | GRIN2D 2888/4885GRIN3B 2052/4885GRIN1 2137/4885 |
| US-20120266392-A1 | PHENYLPYRIDO [1,2-A] INDOLIUM-DERIVED THIOL/DISULFIDE DYE, DYE COMPOSITION COMPRISING THIS DYE, PROCESS FOR LIGHTENING KERATIN MATERIALS USING THIS DYE | KRT18, IK, PTMA | GRIN2D 2387/4885GRIN3B 3761/4885GRIN1 2929/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.