Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.81 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.81 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.81 |
| ▸ | ABL1 | P00519 | 1/20 | 0.69 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.69 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28778540 | 0.88 | PTPN1 (0.63) | PTPN1PTPN2PTPN6ABL1RIN1 | |
| SCHEMBL12648835 | 0.88 | PTPN2 (0.83) | PTPN1PTPN2PTPN6ABL1RIN1 | |
| SCHEMBL29716354 | 0.88 | PTPN2 (0.77) | PTPN1PTPN2PTPN6ABL1RIN1 | |
| SCHEMBL13707509 | 0.87 | PTPN2 (0.81) | PTPN1PTPN2PTPN6ABL1RIN1 | |
| SCHEMBL8283575 | 0.87 | PTPN2 (0.81) | PTPN1PTPN2PTPN6ABL1RIN1 | |
| SCHEMBL2378725 | 0.87 | PTPN2 (0.81) | PTPN1PTPN2PTPN6ABL1RIN1 | |
| SCHEMBL193294 | 0.87 | RAB9A (0.65) | PTPN1PTPN2PTPN6ABL1RIN1 | |
| SCHEMBL193295 | 0.87 | RAB9A (0.65) | PTPN1PTPN2PTPN6ABL1RIN1 | |
| SCHEMBL3557554 | 0.87 | PTPN2 (0.81) | PTPN1PTPN2PTPN6ABL1RIN1 | |
| SCHEMBL1355066 | 0.87 | PTPN2 (0.81) | PTPN1PTPN2PTPN6ABL1RIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104945470-B | Tripeptide epoxy ketone compound constructed by heterocycle, preparation and application | 浙江大学 | 2020-08-11 | — | — | CN | disclosed |