Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.79 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.49 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | UNG | P13051 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.45 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionic Acid SCHEMBL28665177 | 0.90 | ALDH1A1 (0.76) | ALDH1A1GLAPOLBTDP1L3MBTL1 | |
| Ethylene Glycol SCHEMBL27863023 | 0.89 | ALDH1A1 (0.83) | ALDH1A1GLAPOLBTDP1L3MBTL1 | |
| SCHEMBL63361 | 0.89 | ALDH1A1 (1.00) | ALDH1A1GLAPOLBTDP1L3MBTL1 | |
| Terephthalic Acid SCHEMBL11068404 | 0.89 | ALDH1A1 (1.00) | ALDH1A1GLAPOLBTDP1L3MBTL1 | |
| SCHEMBL9806226 | 0.87 | ALDH1A1 (0.86) | ALDH1A1GLAPOLBTDP1L3MBTL1 | |
| SCHEMBL29693000 | 0.87 | ALDH1A1 (0.95) | ALDH1A1GLAPOLBTDP1L3MBTL1 | |
| SCHEMBL8594185 | 0.87 | ALDH1A1 (0.95) | ALDH1A1GLAPOLBTDP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL740726 | 0.87 | ALDH1A1 (0.95) | ALDH1A1GLAPOLBTDP1L3MBTL1 | |
| SCHEMBL8161786 | 0.87 | ALDH1A1 (0.95) | ALDH1A1GLAPOLBTDP1L3MBTL1 | |
| SCHEMBL28508718 | 0.87 | ALDH1A1 (0.95) | ALDH1A1GLAPOLBTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118222064-A | Refrigerator door end cover and production process thereof | 江阴市新万沅机件有限公司 | 2024-06-21 | — | — | CN | claimed |
| CN-112252031-A | Fabric preparation process | 施央浓 | 2021-01-22 | — | — | CN | claimed |
| CN-111519271-B | Preparation process of heat-resistant protective fabric | 杭州润恒医疗器械有限公司 | 2021-01-05 | — | — | CN | claimed |
| CN-111519271-A | Preparation process of heat-resistant protective fabric | 卢再佰 | 2020-08-11 | — | — | CN | claimed |
| CN-118222064-A | Refrigerator door end cover and production process thereof | 江阴市新万沅机件有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-112252031-A | Fabric preparation process | 施央浓 | 2021-01-22 | — | — | CN | disclosed |
| CN-111519271-B | Preparation process of heat-resistant protective fabric | 杭州润恒医疗器械有限公司 | 2021-01-05 | — | — | CN | disclosed |
| CN-111519271-A | Preparation process of heat-resistant protective fabric | 卢再佰 | 2020-08-11 | — | — | CN | disclosed |