Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.40 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7796592 | 0.80 | MAPT (0.37) | LPAR3LPAR1LPAR2S1PR2S1PR1 | |
| SCHEMBL4271904 | 0.79 | S1PR2 (0.40) | EPHX1S1PR2S1PR1S1PR3FAAH | |
| SCHEMBL27746062 | 0.79 | S1PR2 (0.40) | EPHX1S1PR2S1PR1S1PR3FAAH | |
| SCHEMBL7105161 | 0.73 | MEN1 (0.40) | TSHR | |
| SCHEMBL5050593 | 0.73 | CA12 (0.33) | — | |
| SCHEMBL3970116 | 0.72 | TSHR (0.39) | FAAHTSHR | |
| SCHEMBL12503916 | 0.72 | KDM4E (0.30) | — | |
| SCHEMBL5162103 | 0.71 | LPAR3 (0.44) | LPAR3LPAR1LPAR2 | |
| SCHEMBL7797100 | 0.70 | LPAR5 (0.46) | LPAR3LPAR1LPAR2LPAR5PLA2G2C | |
| SCHEMBL4282571 | 0.69 | CA1 (0.46) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111909231-A | 2 ' and/or 5 ' -amino acid ester phosphoramidate 3 ' -deoxyadenosine derivatives as anticancer compounds | 努卡那有限公司 | 2020-11-10 | — | — | CN | disclosed |
| CN-107207554-B | 2 ' and/or 5 ' -amino acid ester phosphoramidate 3 ' -deoxyadenosine derivatives as anticancer compounds | 努卡那有限公司 | 2020-09-11 | — | — | CN | disclosed |
| CN-111527098-A | Phosphoramidate diphosphate salt of nucleoside as anticancer compound | 努卡那公共有限公司 | 2020-08-11 | — | — | CN | disclosed |