Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.44 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.44 |
| ▸ | P2RY10 | O00398 | 6/20 | 0.44 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TLR2 | O60603 | 2/20 | 0.39 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.39 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.39 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27579516 | 0.88 | LPAR5 (0.51) | LPAR5LPAR1LPAR3P2RY10PLA2G2C | |
| SCHEMBL7795355 | 0.88 | LPAR5 (0.51) | LPAR5LPAR1LPAR3P2RY10PLA2G2C | |
| SCHEMBL27554230 | 0.86 | P2RY10 (0.45) | LPAR5LPAR1LPAR3P2RY10PLA2G2C | |
| SCHEMBL7027227 | 0.78 | P2RY10 (0.38) | P2RY10CYP3A4GPR34 | |
| SCHEMBL28954689 | 0.76 | HTT (0.54) | LPAR5LPAR1LPAR3P2RY10PLA2G2C | |
| SCHEMBL14174568 | 0.74 | ALDH1A1 (0.47) | PLA2G2CHTTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL25354441 | 0.74 | P2RY10 (0.54) | LPAR5P2RY10PLA2G2CHTTCYP1A2 | |
| SCHEMBL25354445 | 0.74 | P2RY10 (0.54) | LPAR5P2RY10PLA2G2CHTTCYP1A2 | |
| SCHEMBL12203832 | 0.73 | P2RY10 (0.56) | LPAR5P2RY10PLA2G2CHTTCYP1A2 | |
| SCHEMBL25055940 | 0.73 | MAPT (0.44) | P2RY10PLA2G2CHTTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010031745-A1 | Antiviral purine derivatives | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2001-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010031745-A1 | Antiviral purine derivatives | PNP, TYMP, MTAP | LPAR5 1905/4885LPAR1 1133/4885LPAR3 1997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.