Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HBB | P68871 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL9614727 | 0.96 | — | — | |
| Bicarbonate SCHEMBL9137014 | 0.92 | MEN1 (0.46) | MEN1KMT2ACA5ACA5BCA1 | |
| Bicarbonate SCHEMBL27702283 | 0.92 | MEN1 (0.46) | MEN1KMT2ACA5ACA5BCA1 | |
| Bicarbonate SCHEMBL11643635 | 0.92 | MEN1 (0.46) | MEN1KMT2ACA5ACA5BCA1 | |
| Bicarbonate SCHEMBL29286967 | 0.92 | MEN1 (0.46) | MEN1KMT2ACA5ACA5BCA1 | |
| Bicarbonate SCHEMBL11334598 | 0.92 | MEN1 (0.46) | MEN1KMT2ACA5ACA5BCA1 | |
| Bicarbonate SCHEMBL8546116 | 0.92 | MEN1 (0.46) | MEN1KMT2ACA5ACA5BCA1 | |
| Bicarbonate SCHEMBL20740773 | 0.92 | MEN1 (0.46) | MEN1KMT2ACA5ACA5BCA1 | |
| Bicarbonate SCHEMBL28125256 | 0.88 | MEN1 (0.43) | MEN1KMT2ACA5ACA5BCA1 | |
| Bicarbonate SCHEMBL11287089 | 0.87 | MEN1 (0.50) | MEN1KMT2ACA5ACA5BCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113291019-A | Antibacterial and anti-mosquito aramid fabric and preparation method thereof | 上海铭茜实业有限公司 | 2021-08-24 | — | — | CN | claimed |
| CN-111705505-A | Preparation method of medical protective clothing antibacterial fabric | 湖南臻和亦康医疗用品有限公司 | 2020-09-25 | — | — | CN | claimed |
| CN-113652864-A | Anti-mosquito bacteriostatic sun-proof fabric and preparation method thereof | 苏州同构科技有限公司 | 2021-11-16 | — | — | CN | disclosed |
| CN-113291019-A | Antibacterial and anti-mosquito aramid fabric and preparation method thereof | 上海铭茜实业有限公司 | 2021-08-24 | — | — | CN | disclosed |
| CN-112708957-A | Manufacturing process of antibacterial material for medical protective clothing | 杨漫漫 | 2021-04-27 | — | — | CN | disclosed |
| CN-111705505-A | Preparation method of medical protective clothing antibacterial fabric | 湖南臻和亦康医疗用品有限公司 | 2020-09-25 | — | — | CN | disclosed |
| CN-111705505-A | Preparation method of medical protective clothing antibacterial fabric | 湖南臻和亦康医疗用品有限公司 | 2020-09-25 | — | — | CN | disclosed |