Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 15/20 | 0.67 |
| ▸ | IDO1 | P14902 | 5/20 | 0.60 |
| ▸ | TDO2 | P48775 | 5/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28455653 | 0.88 | FBP1 (0.54) | FBP1IDO1TDO2 | |
| SCHEMBL28844565 | 0.85 | IDO1 (0.81) | FBP1IDO1TDO2 | |
| SCHEMBL29865054 | 0.85 | IDO1 (0.81) | FBP1IDO1TDO2 | |
| SCHEMBL28168853 | 0.85 | FBP1 (0.74) | FBP1IDO1TDO2 | |
| SCHEMBL29865129 | 0.84 | IDO1 (0.76) | FBP1IDO1TDO2 | |
| SCHEMBL28844667 | 0.84 | IDO1 (0.76) | FBP1IDO1TDO2 | |
| SCHEMBL28471007 | 0.83 | FBP1 (0.77) | FBP1 | |
| SCHEMBL28467776 | 0.82 | FBP1 (0.70) | FBP1IDO1TDO2 | |
| SCHEMBL28463675 | 0.82 | FBP1 (0.83) | FBP1IDO1TDO2 | |
| SCHEMBL28457814 | 0.81 | FBP1 (0.81) | FBP1IDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107098846-B | N-acyl sulfonamide FBPase inhibitor, preparation method thereof, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2020-10-09 | — | — | CN | disclosed |