SCHEMBL28458066

SCHEMBL28458066

CCOC(=O)c1cc2c(Nc3ccc(C)cc3)ccc([N+](=O)[O-])c2[nH]1

nearest known ligand 0.75

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 20/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28463229 0.93 FBP1 (0.72) FBP1
SCHEMBL28455689 0.92 FBP1 (0.63) FBP1
SCHEMBL28459973 0.92 FBP1 (0.63) FBP1
SCHEMBL28469977 0.92 FBP1 (0.66) FBP1
SCHEMBL28898873 0.91 FBP1 (0.64) FBP1
SCHEMBL28461224 0.90 FBP1 (0.60) FBP1
SCHEMBL28461147 0.89 FBP1 (0.60) FBP1
SCHEMBL28461701 0.89 FBP1 (0.74) FBP1
SCHEMBL28898860 0.89 FBP1 (0.76) FBP1
SCHEMBL28457817 0.88 FBP1 (0.58) FBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107098846-B N-acyl sulfonamide FBPase inhibitor, preparation method thereof, pharmaceutical composition and application thereof 中国医学科学院药物研究所 2020-10-09 CN disclosed