Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.45 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7230945 | 0.83 | PDE4D (0.64) | CYP2A6MAPTTDP1MAPK1L3MBTL1 | |
| SCHEMBL18449560 | 0.81 | IDO1 (0.50) | MAPTTDP1MAPK1L3MBTL1IDO1 | |
| SCHEMBL18483170 | 0.81 | ACHE (0.53) | MAPTTDP1MAPK1L3MBTL1IDO1 | |
| SCHEMBL28417525 | 0.80 | MAPT (0.51) | MAPTTDP1MAPK1IDO1KMT2A | |
| SCHEMBL18448000 | 0.80 | IDO1 (0.48) | MAPTTDP1MAPK1IDO1KMT2A | |
| SCHEMBL18448504 | 0.79 | ACHE (0.64) | MAPTMAPK1L3MBTL1IDO1KMT2A | |
| SCHEMBL19240302 | 0.79 | ACHE (0.48) | MAPTMAPK1L3MBTL1IDO1KMT2A | |
| SCHEMBL18447787 | 0.77 | KMT2A (0.55) | MAPTMAPK1L3MBTL1IDO1KMT2A | |
| SCHEMBL28881804 | 0.77 | ACHE (0.46) | MAPTTDP1IDO1KMT2AACHE | |
| SCHEMBL4906925 | 0.76 | TDP1 (0.59) | MAPTTDP1MAPK1L3MBTL1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111533684-A | Method for alkenylating pyridine compound | 四川大学 | 2020-08-14 | — | — | CN | claimed |
| CN-111533684-B | Method for alkenylating pyridine compound | 四川大学 | 2021-10-29 | — | — | CN | disclosed |
| CN-111533684-A | Method for alkenylating pyridine compound | 四川大学 | 2020-08-14 | — | — | CN | disclosed |