Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 6/20 | 0.48 |
| ▸ | LTA4H | P09960 | 4/20 | 0.44 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28989843 | 0.97 | FKBP1A (0.50) | FKBP1ALTA4HSLC6A1ACESMN1; SMN2 | |
| SCHEMBL28450788 | 0.97 | FKBP1A (0.50) | FKBP1ALTA4HSLC6A1ACESMN1; SMN2 | |
| SCHEMBL28450790 | 0.97 | FKBP1A (0.50) | FKBP1ALTA4HSLC6A1ACESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL29157417 | 0.96 | FKBP1A (0.49) | FKBP1ALTA4HSLC6A1ACESMN1; SMN2 | |
| SCHEMBL28456592 | 0.87 | SPHK1 (0.48) | FKBP1ASMN1; SMN2 | |
| SCHEMBL28503426 | 0.87 | SPHK1 (0.48) | FKBP1ASMN1; SMN2 | |
| Oxalic Acid SCHEMBL28455046 | 0.86 | POLB (0.58) | FKBP1APOLBSMN1; SMN2ALDH1A1 | |
| Oxalic Acid SCHEMBL28447422 | 0.86 | POLB (0.58) | FKBP1APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL28458446 | 0.85 | FKBP1A (0.52) | FKBP1APOLB | |
| SCHEMBL28456852 | 0.83 | FKBP1A (0.56) | FKBP1APOLBSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107941944-B | Detection method of (2S,5R) -benzyloxyaminopiperidine-2-ethyl formate oxalate | 中山奕安泰医药科技有限公司 | 2020-09-15 | — | — | CN | disclosed |