Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28534889 | 0.76 | NPC1 (0.52) | ATMGAARAB9ANPC1POLB | |
| SCHEMBL28761047 | 0.66 | ALOX5AP (0.43) | — | |
| SCHEMBL28761043 | 0.66 | ALOX5AP (0.43) | — | |
| SCHEMBL10011800 | 0.63 | MEN1 (0.49) | MAPTATMGAARAB9ANPC1 | |
| SCHEMBL10011802 | 0.63 | MEN1 (0.49) | MAPTATMGAARAB9ANPC1 | |
| SCHEMBL28521757 | 0.61 | MEN1 (0.50) | MAPTATMGAAAPOBEC3GMEN1 | |
| SCHEMBL22017068 | 0.61 | MAPT (0.54) | MAPTATMGAARAB9ANPC1 | |
| SCHEMBL20834834 | 0.61 | LMNA (0.49) | MAPTATMGAARAB9ANPC1 | |
| SCHEMBL28528912 | 0.61 | KDM4E (0.46) | MAPTATMGAAPOLBAPOBEC3G | |
| SCHEMBL28527048 | 0.60 | KMT2A (0.47) | MAPTATMGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107162994-B | 4H-1, 2, 4-triazole-3-thiol derivative and preparation method and application thereof | 浙江师范大学行知学院 | 2020-08-14 | — | — | CN | claimed |
| CN-107162994-B | 4H-1, 2, 4-triazole-3-thiol derivative and preparation method and application thereof | 浙江师范大学行知学院 | 2020-08-14 | — | — | CN | disclosed |