Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 9/20 | 0.56 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.56 |
| ▸ | PDE4C | Q08493 | 9/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 9/20 | 0.56 |
| ▸ | PDE3B | Q13370 | 7/20 | 0.56 |
| ▸ | PDE3A | Q14432 | 7/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29696584 | 1.00 | PDE4A (0.56) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL29696619 | 0.92 | ESR1 (0.48) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL28458542 | 0.92 | ESR1 (0.48) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL28454854 | 0.91 | TP53 (0.52) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL29696606 | 0.91 | CNR2 (0.48) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL29696587 | 0.91 | TP53 (0.52) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL28462417 | 0.91 | CNR2 (0.48) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL8939296 | 0.90 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL29696599 | 0.88 | HTR6 (0.46) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL28466760 | 0.88 | HTR6 (0.46) | PDE4APDE4BPDE4CPDE4DPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111533729-B | Tetrazole-substituted quinolinone derivative and preparation method and application thereof | 盐城工学院 | 2022-07-26 | — | — | CN | disclosed |
| CN-111533729-A | Tetrazole-substituted quinolinone derivative and preparation method and application thereof | 盐城工学院 | 2020-08-14 | — | — | CN | disclosed |