Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.41 |
| ▸ | GAPDH | P04406 | 1/20 | 0.41 |
| ▸ | FASN | P49327 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 3/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | GMNN | O75496 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11155763 | 0.84 | TSHR (0.86) | ALDH1A1TSHRMAPTTRPA1DDAH1 | |
| SCHEMBL17627772 | 0.84 | TSHR (0.86) | ALDH1A1TSHRMAPTTRPA1DDAH1 | |
| SCHEMBL11155770 | 0.84 | TSHR (0.86) | ALDH1A1TSHRMAPTTRPA1DDAH1 | |
| SCHEMBL230878 | 0.84 | TSHR (0.86) | ALDH1A1TSHRMAPTTRPA1DDAH1 | |
| SCHEMBL3112313 | 0.84 | TSHR (0.86) | ALDH1A1TSHRMAPTTRPA1DDAH1 | |
| SCHEMBL11155765 | 0.84 | TSHR (0.86) | ALDH1A1TSHRMAPTTRPA1DDAH1 | |
| SCHEMBL309970 | 0.84 | TSHR (0.86) | ALDH1A1TSHRMAPTTRPA1DDAH1 | |
| SCHEMBL3123073 | 0.84 | TSHR (0.86) | ALDH1A1TSHRMAPTTRPA1DDAH1 | |
| SCHEMBL230877 | 0.84 | TSHR (0.86) | ALDH1A1TSHRMAPTTRPA1DDAH1 | |
| SCHEMBL27092728 | 0.84 | TSHR (0.86) | ALDH1A1TSHRMAPTTRPA1DDAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111264486-A | Tilapia bait essence and preparation method thereof | 上海海洋大学 | 2020-06-12 | — | — | CN | claimed |
| CN-111264486-A | Tilapia bait essence and preparation method thereof | 上海海洋大学 | 2020-06-12 | — | — | CN | disclosed |