Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.86 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.86 |
| ▸ | FASN | P49327 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 4/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | F3 | P13726 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.38 |
| ▸ | GAPDH | P04406 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11155770 | 1.00 | TSHR (0.86) | TSHRALDH1A1FASNFAAHTRPV1 | |
| SCHEMBL27092728 | 1.00 | TSHR (0.86) | TSHRALDH1A1FASNFAAHTRPV1 | |
| SCHEMBL230877 | 1.00 | TSHR (0.86) | TSHRALDH1A1FASNFAAHTRPV1 | |
| SCHEMBL11155763 | 1.00 | TSHR (0.86) | TSHRALDH1A1FASNFAAHTRPV1 | |
| SCHEMBL17627772 | 1.00 | TSHR (0.86) | TSHRALDH1A1FASNFAAHTRPV1 | |
| SCHEMBL3112313 | 1.00 | TSHR (0.86) | TSHRALDH1A1FASNFAAHTRPV1 | |
| SCHEMBL11155765 | 1.00 | TSHR (0.86) | TSHRALDH1A1FASNFAAHTRPV1 | |
| SCHEMBL230878 | 1.00 | TSHR (0.86) | TSHRALDH1A1FASNFAAHTRPV1 | |
| SCHEMBL309970 | 1.00 | TSHR (0.86) | TSHRALDH1A1FASNFAAHTRPV1 | |
| SCHEMBL16162666 | 0.93 | TSHR (0.83) | TSHRALDH1A1FASNFAAHTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399489-B2 | Antibacterial piperdine derivatives | ASTRAZENECA AB (GB) | 2013-03-19 | — | — | US | disclosed |
| US-20100179150-A1 | ANTIBACTERIAL PIPERDINE DERIVATIVES | ASTRAZENECA AB (SE) | 2010-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100179150-A1 | ANTIBACTERIAL PIPERDINE DERIVATIVES | PIR, HAMP, AMPD2 | TSHR 4102/4885ALDH1A1 502/4885FASN 1883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.