Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28167515 | 0.90 | ABCG2 (0.54) | ABCG2KDM4EALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL28455071 | 0.86 | KMT2A (0.62) | ABCG2KDM4EALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL28466563 | 0.84 | RET (0.58) | KDM4EALDH1A1CYP3A4HSD17B10CA1 | |
| SCHEMBL6978312 | 0.82 | PTGS2 (0.60) | ABCG2KDM4EALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL28459354 | 0.82 | ABCG2 (0.64) | ABCG2KDM4EALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL28579992 | 0.82 | MAOB (0.62) | ABCG2KDM4EALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL6978404 | 0.80 | PTGS2 (0.60) | KDM4ECA1CA2MEN1KMT2A | |
| SCHEMBL4650702 | 0.78 | ABCG2 (1.00) | ABCG2KDM4EALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL27404210 | 0.77 | ABCG2 (0.76) | ABCG2KDM4EALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL6971109 | 0.76 | PTGS2 (0.65) | ABCG2KDM4EALDH1A1CYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111635387-B | Synthesis method of chromone derivative | 都创(上海)医药科技股份有限公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-111635387-A | Synthesis method of chromone derivative | 都创(上海)医药科技有限公司 | 2020-09-08 | — | — | CN | disclosed |