SCHEMBL284596

SCHEMBL284596

C(=C(c1ccccc1)n1nccn1)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 6/20 0.44
CYP11B2 P19099 2/20 0.44
AKR1C1 Q04828 1/20 0.41
PRMT1 Q99873 1/20 0.38
ESR1 P03372 1/20 0.37
ALDH1A1 P00352 3/20 0.36
MEN1 O00255 2/20 0.36
HPGD P15428 2/20 0.36
KMT2A Q03164 2/20 0.36
KDM4E B2RXH2 1/20 0.36
LMNA P02545 1/20 0.36
POLB P06746 1/20 0.36
MAPT P10636 1/20 0.36
MAPK1 P28482 1/20 0.36
HTT P42858 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
GAA P10253 1/20 0.35
TSHR P16473 1/20 0.34
AKR1C3 P42330 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11574569 0.79 AKR1C1 (0.40) CYP19A1CYP11B2AKR1C1PRMT1ESR1
SCHEMBL6536929 0.74 HPGD (0.51) AKR1C1PRMT1ESR1MEN1HPGD
SCHEMBL6236285 0.72 AKR1C1 (0.44) CYP19A1CYP11B2AKR1C1PRMT1ESR1
SCHEMBL11817198 0.72 CYP19A1 (0.54) CYP19A1CYP11B2AKR1C1PRMT1
SCHEMBL10573027 0.71 HPGD (0.60) AKR1C1ALDH1A1MEN1HPGDKMT2A
SCHEMBL5776078 0.71 HPGD (0.60) AKR1C1ALDH1A1MEN1HPGDKMT2A
SCHEMBL5776074 0.71 HPGD (0.60) AKR1C1ALDH1A1MEN1HPGDKMT2A
SCHEMBL10972659 0.70 AKT1 (0.43) ALDH1A1MEN1HPGDKMT2ALMNA
SCHEMBL285348 0.70 CYP19A1 (0.38) CYP19A1CYP11B2ALDH1A1MEN1HPGD
SCHEMBL9366030 0.69 HPGD (0.63) ALDH1A1MEN1HPGDKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025032504-A2 UV/HEVL-FILTERING SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2025-02-13 WO claimed
US-20250052927-A1 UV/HEVL-FILTERING SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2025-02-13 US claimed
US-11986997-B2 Three-dimensional printing HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2024-05-21 US claimed
US-20220088856-A1 THREE-DIMENSIONAL PRINTING HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2022-03-24 US claimed
US-20210402684-A1 THREE-DIMENSIONAL PRINTING HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2021-12-30 US claimed
WO-2020251532-A1 THREE-DIMENSIONAL PRINTING HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2020-12-17 WO claimed
US-20190015302-A1 FLUORESCENT PARTICULATE MATERIAL L'OREAL (FR) 2019-01-17 US claimed
EP-3397718-A1 FLUORESCENT PARTICULATE MATERIAL L'Oréal (FR) 2018-11-07 EP claimed
WO-2017114877-A1 FLUORESCENT PARTICULATE MATERIAL L'OREAL (FR) 2017-07-06 WO claimed
US-8524621-B2 Metallized flexible laminate material for lighter-than-air vehicles LOCKHEED MARTIN CORPORATION (US) 2013-09-03 US claimed
US-20090042037-A1 Metallized Flexible Laminate Material for Lighter-Than-Air Vehicles LOCKHEED MARTIN CORPORATION 2009-02-12 US claimed
EP-1926591-A1 METALLIZED FLEXIBLE LAMINATE MATERIAL FOR LIGHTER-THAN-AIR VEHICLES Lockheed Martin Corporation (US) 2008-06-04 EP claimed
US-20070221884-A1 Liminescent Silicon Oxide Flakes CIBA SPECIALTY CHEMICALS CORP. 2007-09-27 US claimed
WO-2007038097-A1 METALLIZED FLEXIBLE LAMINATE MATERIAL FOR LIGHTER-THAN-AIR VEHICLES LOCKHEED MARTIN CORPORATION (US) 2007-04-05 WO claimed
EP-1469124-A1 Use of a composition for whitening recycled paper and board pulp De Donato, Fausto (IT) 2004-10-20 EP claimed
EP-1047729-B1 COMPOSITION FOR BLEACHING MECHANICAL PULP DE DONATO FAUSTO (IT) 2003-01-08 EP claimed
EP-1047729-A1 COMPOSITION FOR BLEACHING WOODPULP AND PROCESS FOR ITS PRODUCTION De Donato, Fausto (IT) 2000-11-02 EP claimed
WO-1999029779-A1 COMPOSITION FOR BLEACHING WOODPULP AND PROCESS FOR ITS PRODUCTION DONATO FAUSTO DE (IT) 1999-06-17 WO claimed
US-4276188-A OPTICAL BRIGHTENERS FOR COTTON AND POLYAMIDES CIBA-GEIGY CORPORATION (US) 1981-06-30 US claimed
US-4172045-A Process for the manufacture of 2-stilbenyl-1,2,3-triazoles which contain carboxyl groups, novel 2-stilbenyl-1,2,3-triazoles which contain carboxyl groups and the use thereof as fluorescent brighteners CIBA-GEIGY CORPORATION (US) 1979-10-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190015302-A1 FLUORESCENT PARTICULATE MATERIAL HNRNPM, NPM1, HNRNPF CYP19A1 2754/4885CYP11B2 1541/4885AKR1C1 4126/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.