SCHEMBL6536929

SCHEMBL6536929

C(=C(c1ccccc1)N1CC1)c1ccccc1

nearest known ligand 0.82

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HPGD P15428 5/20 0.51
MAPT P10636 1/20 0.51
CHRM1 P11229 1/20 0.51
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
AKR1C1 Q04828 1/20 0.45
GAA P10253 1/20 0.41
PRMT1 Q99873 1/20 0.41
ESR1 P03372 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5776078 0.92 HPGD (0.60) HPGDMAPTCHRM1MEN1KMT2A
SCHEMBL5776074 0.92 HPGD (0.60) HPGDMAPTCHRM1MEN1KMT2A
SCHEMBL10573027 0.92 HPGD (0.60) HPGDMAPTCHRM1MEN1KMT2A
SCHEMBL9366034 0.90 HPGD (0.63) HPGDMAPTCHRM1MEN1KMT2A
SCHEMBL9366030 0.90 HPGD (0.63) HPGDMAPTCHRM1MEN1KMT2A
SCHEMBL8884084 0.87 RAB9A (0.53) HPGDMAPTMEN1KMT2AGAA
SCHEMBL10419001 0.87 RAB9A (0.53) HPGDMAPTMEN1KMT2AGAA
SCHEMBL12411245 0.79 KMT2A (0.53) HPGDMAPTMEN1KMT2AGAA
SCHEMBL6236285 0.77 AKR1C1 (0.44) HPGDMAPTCHRM1MEN1KMT2A
SCHEMBL7717729 0.76 ALDH1A1 (0.64) HPGDMAPTMEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6696236-B2 SILVER HALIDE GRAINS CONTAIN AT LEAST ONE MEMBER OF A COORDINATION COMPOUND IN WHICH IRIDIUM IS A CENTRAL METAL; PROCESSING SPEED, WHICH OBEYS THE RECIPROCITY RULE AT HIGH-INTENSITY EXPOSURE AND HAS EXCELLENT STABILITY FUJI PHOTO FILM CO. LTD. (JP) 2004-02-24 US disclosed