Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 16/20 | 0.56 |
| ▸ | CNR2 | P34972 | 9/20 | 0.56 |
| ▸ | MARS1 | P56192 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5323965 | 1.00 | CNR1 (0.56) | CNR1CNR2MARS1 | |
| SCHEMBL2845961 | 1.00 | CNR1 (0.56) | CNR1CNR2MARS1 | |
| SCHEMBL5416714 | 0.89 | CNR1 (0.69) | CNR1CNR2MARS1 | |
| SCHEMBL4702795 | 0.89 | CNR1 (0.69) | CNR1CNR2MARS1 | |
| SCHEMBL4702793 | 0.89 | CNR1 (0.69) | CNR1CNR2MARS1 | |
| SCHEMBL14625237 | 0.88 | CNR1 (0.47) | CNR1CNR2MARS1 | |
| SCHEMBL13411482 | 0.88 | CNR1 (0.53) | CNR1CNR2 | |
| SCHEMBL643914 | 0.88 | CNR1 (0.64) | CNR1CNR2MARS1 | |
| SCHEMBL643913 | 0.88 | CNR1 (0.64) | CNR1CNR2MARS1 | |
| SCHEMBL2849871 | 0.88 | CNR1 (0.52) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100069341-A1 | TETRAHYDRO-PYRANOPYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2010-03-18 | — | — | US | claimed |
| US-20070155723-A1 | Tetrahydro-pyranopyrazole cannabinoid modulators | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-07-05 | — | — | US | claimed |
| WO-2007001939-A1 | TETRAHYDRO-PYRANOPYRAZOLE COMPOUNDS DISPLAYING CANNABINOID MODULATING ACTIVITIES | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-01-04 | — | — | WO | claimed |
| US-20100069341-A1 | TETRAHYDRO-PYRANOPYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2010-03-18 | — | — | US | disclosed |
| US-20070155723-A1 | Tetrahydro-pyranopyrazole cannabinoid modulators | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-07-05 | — | — | US | disclosed |
| WO-2007001939-A1 | TETRAHYDRO-PYRANOPYRAZOLE COMPOUNDS DISPLAYING CANNABINOID MODULATING ACTIVITIES | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-01-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155723-A1 | Tetrahydro-pyranopyrazole cannabinoid modulators | CNR2, CNR1, GPR18 | CNR1 2/4885CNR2 1/4885MARS1 4534/4885 |
| US-20100069341-A1 | TETRAHYDRO-PYRANOPYRAZOLE CANNABINOID MODULATORS | CNR2, CNR1, GPR18 | CNR1 2/4885CNR2 1/4885MARS1 4534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.