SCHEMBL28459683

SCHEMBL28459683

C=C(NC(=O)c1ccc(I)cc1)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.46
TPMT P51580 1/20 0.45
NPC1 O15118 3/20 0.44
RAB9A P51151 3/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
HDAC3 O15379 1/20 0.44
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
IDO1 P14902 1/20 0.44
ALOX15 P16050 1/20 0.44
HDAC1 Q13547 1/20 0.44
CA9 Q16790 1/20 0.44
HDAC7 Q8WUI4 1/20 0.44
HDAC2 Q92769 1/20 0.44
HSD17B10 Q99714 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
NCOR2 Q9Y618 1/20 0.44
CTDSP1 Q9GZU7 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6551314 0.89 ALDH1A1 (0.55) ALDH1A1NPC1RAB9AMEN1KMT2A
SCHEMBL28463608 0.82 CCR6 (0.59) ALDH1A1NPC1RAB9AMEN1KMT2A
SCHEMBL28465274 0.82 ALDH1A1 (0.55) ALDH1A1NPC1RAB9AMEN1KMT2A
SCHEMBL31195505 0.82 ALDH1A1 (0.55) ALDH1A1NPC1RAB9AMEN1KMT2A
SCHEMBL28394615 0.82 MEN1 (0.55) ALDH1A1NPC1RAB9AMEN1KMT2A
SCHEMBL28471234 0.82 MEN1 (0.55) ALDH1A1NPC1RAB9AMEN1KMT2A
SCHEMBL31195462 0.82 NPC1 (0.56) ALDH1A1NPC1RAB9AMEN1KMT2A
SCHEMBL28471210 0.82 NPC1 (0.56) ALDH1A1NPC1RAB9AMEN1KMT2A
SCHEMBL28471238 0.79 S1PR4 (0.51) ALDH1A1NPC1RAB9AMEN1KMT2A
SCHEMBL28899288 0.79 KCNK9 (0.56) ALDH1A1NPC1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111747904-A Polyfluoroalkenyl substituted oxazole compound and preparation method thereof 南京工业大学 2020-10-09 CN claimed
CN-111747904-A Polyfluoroalkenyl substituted oxazole compound and preparation method thereof 南京工业大学 2020-10-09 CN disclosed