SCHEMBL284597

SCHEMBL284597

C(=Cc1ccccc1-n1nccn1)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 3/20 0.50
NFE2L2 Q16236 3/20 0.46
TRPA1 O75762 2/20 0.46
CYP11B1 P15538 1/20 0.41
CYP11B2 P19099 1/20 0.41
KDM4E B2RXH2 1/20 0.41
NR1H3 Q13133 5/20 0.40
ATP4A P20648 2/20 0.40
ATP4B P51164 2/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
DHFR P00374 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL284595 1.00 NR1H2 (0.50) NR1H2NFE2L2TRPA1CYP11B1CYP11B2
SCHEMBL31422584 1.00 NR1H2 (0.50) NR1H2NFE2L2TRPA1CYP11B1CYP11B2
SCHEMBL285347 0.90 NR1H2 (0.41) NR1H2NFE2L2NR1H3
SCHEMBL285349 0.86 NR1H2 (0.42) NR1H2NFE2L2TRPA1CYP11B1CYP11B2
Benzo[D]Oxazole SCHEMBL27721294 0.82 NR1H2 (0.38) NR1H2NFE2L2TRPA1KDM4ENR1H3
SCHEMBL8775695 0.80 CHEK1 (0.40) NR1H2NFE2L2TRPA1CYP11B1CYP11B2
SCHEMBL11574572 0.80 NR1H2 (0.45) NR1H2NFE2L2TRPA1KDM4EATP4A
SCHEMBL4163348 0.77 MAPK1 (0.47) NR1H2NFE2L2TRPA1CYP11B1CYP11B2
SCHEMBL4163353 0.77 MAPK1 (0.47) NR1H2NFE2L2TRPA1CYP11B1CYP11B2
SCHEMBL8525606 0.75 CYP11B1 (0.45) NFE2L2TRPA1CYP11B1CYP11B2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 335 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250052927-A1 UV/HEVL-FILTERING SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2025-02-13 US claimed
WO-2025032504-A2 UV/HEVL-FILTERING SILICONE HYDROGEL CONTACT LENSES ALCON INC. (CH) 2025-02-13 WO claimed
US-11986997-B2 Three-dimensional printing HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2024-05-21 US claimed
US-20220088856-A1 THREE-DIMENSIONAL PRINTING HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2022-03-24 US claimed
US-20210402684-A1 THREE-DIMENSIONAL PRINTING HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2021-12-30 US claimed
WO-2020251532-A1 THREE-DIMENSIONAL PRINTING HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2020-12-17 WO claimed
CN-108819530-B High-performance white pigment foil 桐乡市耐箔尔烫印材料有限公司 2020-11-03 CN claimed
US-20190015302-A1 FLUORESCENT PARTICULATE MATERIAL L'OREAL (FR) 2019-01-17 US claimed
EP-3397718-A1 FLUORESCENT PARTICULATE MATERIAL L'Oréal (FR) 2018-11-07 EP claimed
WO-2017114877-A1 FLUORESCENT PARTICULATE MATERIAL L'OREAL (FR) 2017-07-06 WO claimed
US-20090042037-A1 Metallized Flexible Laminate Material for Lighter-Than-Air Vehicles LOCKHEED MARTIN CORPORATION 2009-02-12 US claimed
EP-1926591-A1 METALLIZED FLEXIBLE LAMINATE MATERIAL FOR LIGHTER-THAN-AIR VEHICLES Lockheed Martin Corporation (US) 2008-06-04 EP claimed
US-20070221884-A1 Liminescent Silicon Oxide Flakes CIBA SPECIALTY CHEMICALS CORP. 2007-09-27 US claimed
WO-2007038097-A1 METALLIZED FLEXIBLE LAMINATE MATERIAL FOR LIGHTER-THAN-AIR VEHICLES LOCKHEED MARTIN CORPORATION (US) 2007-04-05 WO claimed
EP-1469124-A1 Use of a composition for whitening recycled paper and board pulp De Donato, Fausto (IT) 2004-10-20 EP claimed
EP-1047729-B1 COMPOSITION FOR BLEACHING MECHANICAL PULP DE DONATO FAUSTO (IT) 2003-01-08 EP claimed
EP-1047729-A1 COMPOSITION FOR BLEACHING WOODPULP AND PROCESS FOR ITS PRODUCTION De Donato, Fausto (IT) 2000-11-02 EP claimed
WO-1999029779-A1 COMPOSITION FOR BLEACHING WOODPULP AND PROCESS FOR ITS PRODUCTION DONATO FAUSTO DE (IT) 1999-06-17 WO claimed
US-4276188-A OPTICAL BRIGHTENERS FOR COTTON AND POLYAMIDES CIBA-GEIGY CORPORATION (US) 1981-06-30 US claimed
US-4172045-A Process for the manufacture of 2-stilbenyl-1,2,3-triazoles which contain carboxyl groups, novel 2-stilbenyl-1,2,3-triazoles which contain carboxyl groups and the use thereof as fluorescent brighteners CIBA-GEIGY CORPORATION (US) 1979-10-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190015302-A1 FLUORESCENT PARTICULATE MATERIAL HNRNPM, NPM1, HNRNPF NR1H2 3205/4885NFE2L2 946/4885TRPA1 45/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.