Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATP4A | P20648 | 2/20 | 0.40 |
| ▸ | ATP4B | P51164 | 2/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CYP24A1 | Q07973 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4163348 | 1.00 | MAPK1 (0.47) | MAPK1NPC1NR1H2NFE2L2TRPA1 | |
| SCHEMBL4155688 | 0.83 | NFE2L2 (0.42) | MAPK1NPC1NFE2L2TRPA1KDM4E | |
| SCHEMBL4155690 | 0.83 | NFE2L2 (0.42) | MAPK1NPC1NFE2L2TRPA1KDM4E | |
| SCHEMBL13351494 | 0.81 | MAPK1 (0.49) | MAPK1NPC1KDM4EALDH1A1MEN1 | |
| SCHEMBL3863178 | 0.79 | NR1H2 (0.42) | NR1H2NFE2L2TRPA1KDM4EATP4A | |
| SCHEMBL8090136 | 0.79 | NR1H2 (0.42) | NR1H2NFE2L2TRPA1KDM4EATP4A | |
| SCHEMBL284595 | 0.77 | NR1H2 (0.50) | NR1H2NFE2L2TRPA1KDM4EMEN1 | |
| SCHEMBL31422584 | 0.77 | NR1H2 (0.50) | NR1H2NFE2L2TRPA1KDM4EMEN1 | |
| SCHEMBL284597 | 0.77 | NR1H2 (0.50) | NR1H2NFE2L2TRPA1KDM4EMEN1 | |
| SCHEMBL613201 | 0.77 | ALDH1A1 (0.51) | MAPK1NPC1KDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172045-A | Process for the manufacture of 2-stilbenyl-1,2,3-triazoles which contain carboxyl groups, novel 2-stilbenyl-1,2,3-triazoles which contain carboxyl groups and the use thereof as fluorescent brighteners | CIBA-GEIGY CORPORATION (US) | 1979-10-23 | — | — | US | claimed |
| US-8212048-B2 | Method of producing aromatic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-07-03 | — | — | US | disclosed |
| CN-101410375-B | Process for producing aromatic compound | SUMITOMO CO LTD | 2012-06-13 | — | — | CN | disclosed |
| CN-101410375-A | Process for producing aromatic compound | SUMITOMO CHEMICAL CO (JP) | 2009-04-15 | — | — | CN | disclosed |
| US-20090043096-A1 | METHOD OF PRODUCING AROMATIC COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090043096-A1 | METHOD OF PRODUCING AROMATIC COMPOUND | AHR, CYP1A1, ARNT | MAPK1 1786/4885NPC1 1177/4885NR1H2 78/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.