Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 5/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1948952 | 0.95 | ALDH1A1 (0.58) | ALDH1A1TSHRATMHCAR2HPGD | |
| SCHEMBL1401947 | 0.95 | ALDH1A1 (0.58) | ALDH1A1TSHRATMHCAR2HPGD | |
| Hydrochloric Acid SCHEMBL10892981 | 0.93 | ALDH1A1 (0.56) | ALDH1A1TSHRATMHCAR2HPGD | |
| Water SCHEMBL27921488 | 0.93 | ALDH1A1 (0.56) | ALDH1A1TSHRATMHCAR2HPGD | |
| Ammonia Solution, Strong SCHEMBL27659655 | 0.93 | ALDH1A1 (0.56) | ALDH1A1TSHRATMHCAR2HPGD | |
| SCHEMBL1401944 | 0.93 | ALDH1A1 (0.56) | ALDH1A1TSHRATMHCAR2HPGD | |
| Hydrazine SCHEMBL1234309 | 0.91 | ALDH1A1 (0.54) | ALDH1A1TSHRATMHCAR2HPGD | |
| Acetic Acid SCHEMBL28461572 | 0.91 | ALDH1A1 (0.65) | ALDH1A1TSHRATMHCAR2HPGD | |
| SCHEMBL368375 | 0.88 | TSHR (0.61) | ALDH1A1TSHRATMHCAR2NAAA | |
| SCHEMBL3028861 | 0.86 | TSHR (0.64) | ALDH1A1TSHRHCAR2NAAARAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111755144-B | Low-temperature conductive silver paste and preparation method and application thereof | 宁波鑫智达新材料有限公司 | 2022-03-22 | — | — | CN | disclosed |
| CN-111755144-A | Low-temperature conductive silver paste and preparation method and application thereof | 海泰纳鑫科技(成都)有限公司 | 2020-10-09 | — | — | CN | disclosed |