Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 5/20 | 0.33 |
| ▸ | HTR1B | P28222 | 5/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | HTR1F | P30939 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 2/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28462259 | 1.00 | HTR1D (0.33) | HTR1DHTR1BHTR1AKMT2AHTR2A | |
| SCHEMBL15905687 | 0.95 | HTR1D (0.32) | HTR1DHTR1BHTR1AKMT2AHTR2A | |
| SCHEMBL5170319 | 0.88 | KCNH2 (0.33) | HTR1DHTR1BHTR1AKMT2AHTR2A | |
| SCHEMBL2155869 | 0.88 | KCNH2 (0.33) | HTR1DHTR1BHTR1AKMT2AHTR2A | |
| SCHEMBL24324048 | 0.88 | KCNH2 (0.33) | HTR1DHTR1BHTR1AKMT2AHTR2A | |
| SCHEMBL28469014 | 0.80 | HTR1D (0.33) | HTR1DHTR1BHTR1AKMT2AHTR2A | |
| SCHEMBL28469012 | 0.80 | HTR1D (0.33) | HTR1DHTR1BHTR1AKMT2AHTR2A | |
| SCHEMBL15905689 | 0.79 | HTR1D (0.32) | HTR1DHTR1BHTR1AKMT2AHTR2A | |
| SCHEMBL8873531 | 0.77 | PLG (0.34) | HTR1DHTR1BHTR1AKMT2AHTR2A | |
| SCHEMBL8873526 | 0.77 | PLG (0.34) | HTR1DHTR1BHTR1AKMT2AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106866502-B | Cathepsin K inhibitors and uses thereof | 广东东阳光药业有限公司 | 2020-10-09 | — | — | CN | disclosed |