Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulconazole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 10/20 | 0.98 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.98 |
| ▸ | CYP2C9 | P11712 | 9/20 | 0.98 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.98 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.98 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.98 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.98 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.98 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.98 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.98 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.98 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.98 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.98 |
| ▸ | DRD3 | P35462 | 4/20 | 0.98 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.98 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.98 |
| ▸ | USP2 | O75604 | 3/20 | 0.98 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.98 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.98 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.98 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulconazole SCHEMBL34762 | 0.99 | IDO1 (1.00) | IDO1CYP3A4CYP2C9CYP1A2CYP2D6 | |
| Sulconazole SCHEMBL7600689 | 0.99 | IDO1 (1.00) | IDO1CYP3A4CYP2C9CYP1A2CYP2D6 | |
| Sulconazole SCHEMBL34761 | 0.99 | IDO1 (1.00) | IDO1CYP3A4CYP2C9CYP1A2CYP2D6 | |
| Sulconazole SCHEMBL22123404 | 0.99 | IDO1 (1.00) | IDO1CYP3A4CYP2C9CYP1A2CYP2D6 | |
| Sulconazole SCHEMBL7600685 | 0.99 | IDO1 (1.00) | IDO1CYP3A4CYP2C9CYP1A2CYP2D6 | |
| Sulconazole SCHEMBL29923838 | 0.99 | IDO1 (1.00) | IDO1CYP3A4CYP2C9CYP1A2CYP2D6 | |
| Sulconazole SCHEMBL29194304 | 0.98 | IDO1 (0.98) | IDO1CYP3A4CYP2C9CYP1A2CYP2D6 | |
| SCHEMBL11699369 | 0.92 | IDO1 (0.87) | IDO1CYP3A4CYP2C9CYP1A2CYP2D6 | |
| SCHEMBL11698496 | 0.92 | IDO1 (0.87) | IDO1CYP3A4CYP2C9CYP1A2CYP2D6 | |
| SCHEMBL11693931 | 0.92 | IDO1 (0.87) | IDO1CYP3A4CYP2C9CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111700878-A | Drug nanoparticles exhibiting enhanced mucosal transport | 卡拉制药公司 | 2020-09-25 | — | — | CN | disclosed |
| CN-111700880-A | Drug nanoparticles exhibiting enhanced mucosal transport | 卡拉制药公司 | 2020-09-25 | — | — | CN | disclosed |