SCHEMBL284634

SCHEMBL284634

CCc1cccc2c1nnn2CC

nearest known ligand 0.65

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 15/20 0.65
SLC9A1 P19634 2/20 0.53
TLR8 Q9NR97 1/20 0.40
HCAR3 P49019 1/20 0.40
TOP2A P11388 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27857285 0.86 GRM2 (0.49) GRM2SLC9A1TLR8
SCHEMBL5016075 0.82 GRM2 (0.56) GRM2SLC9A1
SCHEMBL17828279 0.80 GRM2 (0.67) GRM2SLC9A1TLR8
SCHEMBL19018311 0.80 SLC9A1 (0.46) GRM2SLC9A1TLR8HCAR3
SCHEMBL14075470 0.79 GRM2 (0.52) GRM2SLC9A1
SCHEMBL29071338 0.79 ATM (0.44) GRM2SLC9A1TLR8
SCHEMBL14877074 0.78 GRM2 (0.41) GRM2SLC9A1TLR8
SCHEMBL27861443 0.75 GRM2 (0.39) GRM2SLC9A1TLR8
SCHEMBL19990152 0.71 GRM2 (0.44) GRM2
SCHEMBL14443296 0.70 GRM2 (0.50) GRM2SLC9A1HCAR3TOP2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116606685-A Water-soluble temper rolling liquid composition for non-degreased annealed steel sheet 大同化学株式会社 2023-08-18 CN claimed
US-12180410-B2 Thermal management system SHELL USA, INC. (US) 2024-12-31 US disclosed
EP-4127116-B1 MANAGING THERMAL RUNAWAY SHELL INT RESEARCH (NL) 2024-04-10 EP disclosed
EP-4127115-B1 THERMAL MANAGEMENT SYSTEM SHELL INT RESEARCH (NL) 2023-11-15 EP disclosed
CN-116606685-A Water-soluble temper rolling liquid composition for non-degreased annealed steel sheet 大同化学株式会社 2023-08-18 CN disclosed
US-20230097290-A1 THERMAL MANAGEMENT SYSTEM SHELL USA, INC. 2023-03-30 US disclosed
EP-4127115-A1 THERMAL MANAGEMENT SYSTEM Shell Internationale Research Maatschappij B.V. (NL) 2023-02-08 EP disclosed
EP-4127116-A1 MANAGING THERMAL RUNAWAY Shell Internationale Research Maatschappij B.V. (NL) 2023-02-08 EP disclosed
CN-115349010-A Managing thermal runaway 国际壳牌研究有限公司 2022-11-15 CN disclosed
CN-115335497-A Thermal management system 国际壳牌研究有限公司 2022-11-11 CN disclosed
EP-1893729-A1 ELECTRICAL OIL FORMULATION Shell Internationale Research Maatschappij B.V. (NL) 2008-03-05 EP disclosed
US-20070275865-A1 Refrigerating Machine Oil NIPPON OIL CORPORATION (JP) 2007-11-29 US disclosed
US-20070257229-A1 Refrigerating Machine Oil Composition NIPPON OIL CORPORATION (JP) 2007-11-08 US disclosed
US-20070032391-A1 Refrigerating machine oil composition NIPPON OIL CORPORATION (JP) 2007-02-08 US disclosed
WO-2006136591-A1 OXIDATIVE STABLE OIL FORMULATION SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2006-12-28 WO disclosed
WO-2006136594-A1 ELECTRICAL OIL FORMULATION SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2006-12-28 WO disclosed
EP-1734103-A1 LUBRICATING OIL COMPOSITION FOR INDUSTRIAL MACHINERY AND EQUIPMENT Nippon Oil Corporation (JP) 2006-12-20 EP disclosed
US-5912212-A OIL WITH 3-METHYL-5-TERT-BUTYL-4-HYDROXYPHENYL FATTY ESTER, SULFUR AND PHOSPHORUS NIPPON OIL CO., LTD. (JP) 1999-06-15 US disclosed
EP-0781834-A2 Lubricating oil composition NIPPON OIL CO. LTD. (JP) 1997-07-02 EP disclosed
US-4642221-A AROMATIC TRIAZOLES AND IMINODICARBOXYLIC ACID DERIVATIVES ATLANTIC RICHFIELD COMPANY (US) 1987-02-10 US disclosed